Cancer remains the second leading cause of mortality worldwide. In the course of this
multistage and multifactorial disease, a set of alterations takes place, with genetic and …

Obesity is a leading contributing factor to cancer development worldwide. Epidemiological
evidence suggests that diet affects cancer risk and also substantially alters therapeutic …

Excess adiposity is a risk factor for several cancer types. This is likely due to complex
mechanisms including alterations in the lipid milieu that plays a pivotal role in multiple …

Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest
in recent years in such areas as energy sources, cell membrane components, and signaling …

Currently, there is renewed interest in elucidating the metabolic characteristics of cancer and
how these characteristics may be exploited as therapeutic targets. Much attention has …

The disorder of lipid metabolism is pathologically linked to hyperlipidemia, lipid storage
disease, obesity and other related diseases. Intriguingly, recent studies have revealed that …

Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …

Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

Fatty acids are closely involved in lipid synthesis and metabolism in cancer. Their amount
and composition are dependent on dietary supply and tumor microenviroment. Research in …

Over the past decade, the study of metabolic abnormalities in cancer cells has risen
dramatically. Cancer cells can thrive in challenging environments, be it the hypoxic and …