BACKGROUND: Bronchiolitis obliterans syndrome is the main long-term complication of
lung transplantation that limits survival of lung transplant patients. Its pathophysiologic …

Background. Obliterative bronchiolitis (OB), the most important long-term complication after
lung transplantation, is thought to be a manifestation of chronic rejection within the airways …

Background. The major limitation to survival after lung transplantation is bronchiolitis
obliterative syndrome (BOS). BOS is a chronic inflammatory/immunologic process …

BACKGROUND: We hypothesized that immune mediator concentrations in the
bronchoalveolar fluid (BALF) are predictive of bronchiolitis obliterans syndrome (BOS) and …

Bronchiolitis obliterans syndrome (BOS), a condition of irreversible small airway fibrosis, is
the principal factor limiting long-term survival after lung transplantation. Bronchoscopy and …

BACKGROUND The bronchiolitis obliterans syndrome (BOS) remains the major constraint
on the long term success of lung transplantation. Neutrophils have been associated with …

Objective: This study identifies specific clinical and immunologic factors in lung transplant
recipients that influence the subsequent development of chronic allograft dysfunction …

The major cause of mortality in the long-term in lung transplant recipients is chronic
rejection. This is a fibroproliferative process in the small airways leading to obliterative …

Background Acute rejection has emerged as an important risk factor for obliterative
bronchiolitis after lung transplantation. We performed a multivariate analysis to assess the …

BACKGROUND: The mechanisms that lead to the fibrotic obliteration in bronchiolitis
obliterans syndrome (BOS) may involve the interactions between T-helper (Th) 1 and Th2 …