The difficulty of the molecular design and chemical synthesis of artificial sensing receptors
restricts their diagnostic and proteomic applications. Herein, we report a concept of …

Aptamers are single-stranded oligonucleotides that can be artificially generated by a method
called Systematic evolution of ligands by exponential enrichment (SELEX). The generated …

Nucleic acid aptamers are small sequences of DNA made via in vitro selection techniques to
bind targets with high affinity and specificity. The term aptamer derives from the Latin, aptus …

Nucleic acid aptamers are an emerging class of synthetic ligands and have recently
attracted significant attention in numerous fields. One is in biosensor development. In …

Aptamers are nucleic acid-based affinity reagents that have gained widespread attention as
biorecognition elements for the detection of targets such as ions, small molecules, and …

Aptamers are chemically synthesized oligonucleotides or peptides with molecular
recognition capabilities. We investigated recognition of substrate-tethered small-molecule …

Aptamers comprise a range of molecular recognition scaffolds that can be engineered to
bind to a legion of different proteins and other targets with excellent specificity and affinity …

Nucleic acid aptamers are promising alternatives to antibodies in analytics. They are
generally obtained through an iterative SELEX protocol that enriches a population of …

Due to their relative synthetic and chemical simplicity compared to antibodies, aptamers
afford enhanced stability and functionality for the detection of environmental contaminants …

In this work, we report a new concept of adaptive “ensemble aptamers”(ENSaptamers) that
exploits the collective recognition abilities of a small set of rationally designed, nonspecific …