[HTML][HTML] Targeting neuroendocrine abnormalities in Parkinson's disease with exercise

NS Luthra, DD Christou, A Clow… - Frontiers in Neuroscience, 2023 - frontiersin.org
Parkinson's Disease (PD) is a prevalent and complex age-related neurodegenerative
condition for which there are no disease-modifying treatments currently available. The …

Neuroendocrine abnormalities in Parkinson's disease

E De Pablo-Fernández, DP Breen… - Journal of Neurology …, 2017 - jnnp.bmj.com
Neuroendocrine abnormalities are common in Parkinson's disease (PD) and include
disruption of melatonin secretion, disturbances of glucose, insulin resistance and bone …

The role of exercise in facilitating basal ganglia function in Parkinson's disease

GM Petzinger, BE Fisher, G Akopian… - Neurodegenerative …, 2011 - Taylor & Francis
Epidemiological and clinical studies have suggested that exercise is beneficial for patients
with Parkinson's disease (PD). Through research in normal (noninjured) animals …

An overview of the neuroendocrine system in Parkinson's disease: what is the impact on diagnosis and treatment?

A Mulak - Expert Review of Neurotherapeutics, 2020 - Taylor & Francis
Introduction: A growing body of evidence indicates that neuroendocrine interactions may
occur at all levels of the brain-gut-microbiota axis, which is directly involved in the …

[HTML][HTML] The effects of exercise on dopamine neurotransmission in Parkinson's disease: targeting neuroplasticity to modulate basal ganglia circuitry

GM Petzinger, DP Holschneider, BE Fisher… - Brain …, 2015 - content.iospress.com
Animal studies have been instrumental in providing evidence for exercise-induced
neuroplasticity of corticostriatal circuits that are profoundly affected in Parkinson's disease …

[HTML][HTML] The interrelated multifactorial actions of cortisol and klotho: Potential implications in the pathogenesis of parkinson's disease

NS Luthra, A Clow, DM Corcos - Brain Sciences, 2022 - mdpi.com
The pathogenesis of Parkinson's disease (PD) is complex, multilayered, and not fully
understood, resulting in a lack of effective disease-modifying treatments for this prevalent …

[HTML][HTML] Role of physical activity in Parkinson's disease

KS Bhalsing, MM Abbas, LCS Tan - Annals of Indian Academy of …, 2018 - journals.lww.com
Parkinson's disease (PD) is common, age-dependent neurodegenerative disorder caused
by a severe loss of the nigrostriatal dopaminergic neurons. Given the projected increase in …

[HTML][HTML] The emerging role of energy metabolism and neuroprotective strategies in Parkinson's disease

JW Błaszczyk - Frontiers in aging neuroscience, 2018 - frontiersin.org
Over two centuries ago James Parkinson published “An Essay on the Shaking Palsy”
summarizing his experience with neural pathology now known as Parkinson's disease …

We need to move more: Neurobiological hypotheses of physical exercise as a treatment for Parkinson's disease

RS Monteiro-Junior, T Cevada, BRR Oliveira… - Medical hypotheses, 2015 - Elsevier
Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases in the
world. The degeneration of dopaminergic neurons in the substantia nigra and chronic …

[HTML][HTML] The EXPANd trial: effects of exercise and exploring neuroplastic changes in people with Parkinson's disease: a study protocol for a double-blinded …

E Franzén, H Johansson, M Freidle, U Ekman… - BMC neurology, 2019 - Springer
Background Parkinson's disease (PD) affects many physiological systems essential for
balance control. Recent studies suggest that intensive and cognitively demanding physical …