Immunomodulatory nanosystems

X Feng, W Xu, Z Li, W Song, J Ding… - Advanced science, 2019 - Wiley Online Library
Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

Nano-immunotherapy: Unique mechanisms of nanomaterials in synergizing cancer immunotherapy

Q Liu, Y Duo, J Fu, M Qiu, Z Sun, D Adah, J Kang, Z Xie… - Nano Today, 2021 - Elsevier
Therapeutic targeting of the immune system, including chimeric antigen receptor-T cell
therapy, immune checkpoint blockade therapy, neoantigen vaccines, and small molecule …

Biomedical nanomaterials for immunological applications: ongoing research and clinical trials

V Lenders, X Koutsoumpou, A Sargsian… - Nanoscale …, 2020 - pubs.rsc.org
Research efforts on nanomaterial-based therapies for the treatment of autoimmune diseases
and cancer have spiked and have made rapid progress over the past years. Nanomedicine …

Immunomodulating nanomedicine for cancer therapy

Z Liu, W Jiang, J Nam, JJ Moon, BYS Kim - Nano letters, 2018 - ACS Publications
Nanomaterials offer unique advantages as drug-delivery vehicles for cancer therapeutics.
For immuno-oncology applications, cancer nanomedicine should be developed beyond …

Nanoparticles for immune stimulation against infection, cancer, and autoimmunity

S Singha, K Shao, KK Ellestad, Y Yang, P Santamaria - ACS nano, 2018 - ACS Publications
Vaccination using nanocarrier-based delivery systems has recently emerged as a promising
approach for meeting the continued challenge posed by infectious diseases and cancer. A …

Nanoparticles and direct immunosuppression

TA Ngobili, MA Daniele - Experimental biology and …, 2016 - journals.sagepub.com
Targeting the immune system with nanomaterials is an intensely active area of research.
Specifically, the capability to induce immunosuppression is a promising complement for …

Nanoparticle-based immunoengineering strategies for enhancing cancer immunotherapy

BTN Dang, TK Kwon, S Lee, JH Jeong… - Journal of Controlled …, 2024 - Elsevier
Cancer immunotherapy is a groundbreaking strategy that has revolutionized the field of
oncology compared to other therapeutic strategies, such as surgery, chemotherapy, or …

Targeted cancer immunotherapy: nanoformulation engineering and clinical translation

M Yu, W Yang, W Yue, Y Chen - Advanced Science, 2022 - Wiley Online Library
With the rapid growth of advanced nanoengineering strategies, there are great implications
for therapeutic immunostimulators formulated in nanomaterials to combat cancer. It is crucial …

Nanoparticles as smart carriers for enhanced cancer immunotherapy

N Thakur, S Thakur, S Chatterjee, J Das… - Frontiers in Chemistry, 2020 - frontiersin.org
Cancer immunotherapy has emerged as a promising strategy for the treatment of many
forms of cancer by stimulating body's own immune system. This therapy not only eradicates …

Nano-enhanced immunotherapy: Targeting the immunosuppressive tumor microenvironment

Y Jin, Y Huang, H Ren, H Huang, C Lai, W Wang… - Biomaterials, 2024 - Elsevier
The tumor microenvironment (TME), which is mostly composed of tumor cells, immune cells,
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …