Genome engineering of Corynebacterium glutamicum, an important industrial
microorganism for amino acids production, currently relies on random mutagenesis and …

Corynebacterium glutamicum is an important organism for the industrial production of amino
acids. Metabolic pathways in this organism are usually engineered by conventional methods …

Highlights•Corynebacterium glutamicum has been used for many applications beyond
amino acids.•Economical, high-quality genome assemblies foster development of non-type …

Corynebacterium glutamicum has been considered a promising synthetic biological platform
for biomanufacturing and bioremediation. However, there are still some challenges in …

Abstract CRISPR/Cas9 or Cpf1-introduced double strand break dramatically decreases
bacterial cell survival rate, which hampers multiplex genome editing in bacteria. In addition …

Background Corynebacterium glutamicum is an important industrial workhorse and
advanced genetic engineering tools are urgently demanded. Recently, the clustered …

Corynebacterium glutamicum is an important industrial producer of various amino acids with
great potential for the production of other metabolites. The complete genome sequences of …

Targeted top-down strategies for genome reduction are considered to have a high potential
for providing robust basic strains for synthetic biology and industrial biotechnology …

Corynebacterium glutamicum is a major workhorse in industrial biotechnology. For the past
several decades, this soil bacterium has been used to produce the amino acids l-glutamate …

Abstract l-Amino acids find various applications in biotechnology. l-Glutamic acid and its
salts are used as flavor enhancers. Other l-amino acids are used as food or feed additives …