RNA pol II assembly occurs in the cytoplasm before translocation of the enzyme to the
nucleus. Affecting this assembly influences mRNA transcription in the nucleus and mRNA …

Nucleoli are the major cellular compartments for the synthesis of rRNA and assembly of
ribosomes, the macromolecular complexes responsible for protein synthesis. Given the …

Eukaryotic RNA polymerase II is a complex enzyme composed of 12 distinct subunits that is
present in cells in low abundance. Transcription of mRNA by RNA polymerase II involves a …

Transcription by RNA polymerase II (Pol II) is required to produce mRNAs and some
noncoding RNAs (ncRNAs) within mammalian cells. This coordinated process is precisely …

RNA polymerase II (Pol II) transcribes genes that encode proteins and noncoding small
nuclear RNAs (snRNAs). The carboxyl-terminal repeat domain (CTD) of the largest subunit …

Transcription and co-transcriptional processes, including pre-mRNA splicing and mRNA
cleavage and polyadenylation, regulate the production of mature mRNAs. The carboxyl …

Summary RNA polymerase II (RNA Pol II) subunits are thought to be involved in various
transcription-associated processes, but it is unclear whether they play different regulatory …

Recent evidence suggests a role for the carboxyl-terminal domain (CTD) of the largest
subunit of RNA polymerase II (pol II) in pre-mRNA processing. The yeast NRD1 gene …

Pol II (RNA polymerase II) transcribes the genes encoding proteins and non-coding snRNAs
(small nuclear RNAs). The largest subunit of Pol II contains a distinctive CTD (C-terminal …

Transcription termination by RNA polymerase II (RNA Pol II) is linked to RNA 3′ end
processing by the cleavage and polyadenylation factor (CPF or CPSF). CPF contains …