Background C3 glomerulopathy is a rare and heterogeneous complement-driven disease. It
is often challenging to accurately predict in clinical practice the individual kidney prognosis …

Rationale & Objective A previous study that evaluated associations of kidney biopsy findings
with disease progression in patients with C3 glomerulopathy (C3G) proposed a prognostic …

Introduction The association between a change in proteinuria over time and its impact on
kidney prognosis has not been analysed in complement component 3 (C3) glomerulopathy …

Background Data on prognostic factors of C3 glomerulopathy (C3G) are limited, and
validation of the new C3G histologic index (C3G-HI) in different settings is still needed. We …

One study from Columbia University proposed a histologic scoring index for the assessment
of both disease activity and chronicity parameters in C3G (C3G-HI)[3], with the latter based …

Background C3 glomerulopathy is a rare kidney disease, which makes it difficult to collect
large cohorts of patients to better understand its variability. The aims of this study were to …

C3 glomerulopathy (C3G) is a rare complement-mediated disease. Specific treatments are
not yet available and factors predictive of kidney survival such as age, kidney function and …

Background: Complement 3 glomerulopathy (C3G) is a rare kidney disease, with an
estimated incidence of 1-2/million/year. C3G associates with a high risk of disease …

Abstract C3 glomerulopathy (C3G) is a rare complement-mediated disease. Treatments are
not yet available and factors predictive of renal survival such as age, renal function and …

Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …