Reactive oxygen species (ROS), including H2O2, contribute to oxidative stress and may
cause cancer initiation and progression. However, at low concentrations, H2O2 can regulate …

Aquaporin-5 (AQP5) is a membrane water channel widely distributed in human tissues that
was found up-regulated in different tumors and considered implicated in carcinogenesis in …

Abstract Aquaporin-8 (AQP8) allows the bidirectional transport of water and hydrogen
peroxide across biological membranes. Depending on its concentration, H2O2 exerts …

Most breast cancer mortality is due to clinical relapse associated with metastasis.
CXCL12/CXCR4-dependent cell migration is a critical process in breast cancer progression; …

Abstract Aquaporin (AQP) 9, a member of the transmembrane water channel family, is
defined as a water/glycerol transporting protein. Some AQPs including AQP3 and AQP8 …

Abstract Aquaporin 3 (AQP3), a water/glycerol channel protein, is capable of transporting
hydrogen peroxide (H 2 O 2). Here, we show that AQP3-mediated intracellular H 2 O 2 is …

Increasing evidence suggests that the water/glycerol channel aquaporin-3 (AQP3) plays a
pivotal role in cancer metastasis. AQP3 knockout mice were resistant to skin tumor formation …

Aquaporin (AQP) is a family of transmembrane proteins for water transport. Recent studies
revealed that AQPs are likely to play a role in tumor progression and invasion. We aimed to …

Aquaporins (AQPs) are a family of small transmembrane proteins that selectively transport
water and other small molecules and ions following an osmotic gradient across cell plasma …

As highly conserved ubiquitous proteins, aquaporins (AQPs) play an imperative role in the
development and progression of cancer. By trafficking water and other small molecules …