Standard DXA measurements, including Fracture Risk Assessment Tool (FRAX) scores,
have shown limitations in assessing fracture risk in Type 2 Diabetes (T2D), underscoring the …

Fragility fractures are an important hallmark of aging and an increasingly recognized
complication of Type 2 diabetes (T2D). T2D individuals have been found to exhibit an …

Osteoporosis is the consequence of altered bone metabolism resulting in the systemic
reduction of bone strength and increased risk of fragility fractures. MicroRNAs (miRNAs) …

Osteoporosis as a systemic skeletal disorder is characterized by increased bone fragility and
the risk of fractures. According to the World Health Organization, osteoporosis is one of the …

Type 1 diabetes (T1D) is characterized by bone loss and altered bone remodeling, resulting
into reduction of bone mineral density (BMD) and increased risk of fractures. Identification of …

Context Measurement of circulating microRNAs (miRNAs) as potential biomarkers of fragility
fracture risk has recently become a subject of investigation. Objective Measure by next …

Background MicroRNAs (miRNAs) are important regulators of gene expression, with
documented roles in bone metabolism and osteoporosis, suggesting potential therapeutic …

Osteoporosis is the most common metabolic bone disorder affecting up to 40% of
postmenopausal women, characterized by a reduction in bone mass and strength leading to …

Aging is associated with an increased incidence of age-related bone diseases. Current
diagnostics (eg, conventional radiology, biochemical markers), because limited in specificity …

We previously demonstrated the aberrant expression of nine specific miRNAs in serum from
osteoporotic patients. In the present study, we further evaluated the expression of these …