Removing the physician from the equation: Patient‐controlled, home‐based therapeutic drug self‐monitoring of tacrolimus
M Hazenbroek, LHM Pengel… - British Journal of …, 2024 - Wiley Online Library
The dosing of tacrolimus, which forms the backbone of immunosuppressive therapy after
kidney transplantation, is complex. This is due to its variable pharmacokinetics (both …
kidney transplantation, is complex. This is due to its variable pharmacokinetics (both …
Therapeutic drug monitoring of tacrolimus after kidney transplantation: trough concentration or area under curve‐based monitoring?
T van Gelder, A Gelinck, S Meziyerh… - British Journal of …, 2024 - Wiley Online Library
Measurement of pre‐dose tacrolimus concentrations, also referred to as trough
concentrations or C0 (in this paper the term C0 will be used), is the most frequently used …
concentrations or C0 (in this paper the term C0 will be used), is the most frequently used …
Tacrolimus whole blood concentrations correlate closely to side‐effects in renal transplant recipients
Böttiger, Brattström, Tydén, Säwe… - British journal of clinical …, 1999 - Wiley Online Library
Aims To evaluate the relationship between tacrolimus whole blood concentrations and side‐
effects and rejections in 14 renal transplant recipients. Methods Tacrolimus was measured …
effects and rejections in 14 renal transplant recipients. Methods Tacrolimus was measured …
First clinical experience with the new once-daily formulation of tacrolimus
MR First - Therapeutic drug monitoring, 2008 - journals.lww.com
Once-daily tacrolimus is a new oral formulation of the established immunosuppressive agent
tacrolimus (Prograf, Astellas Pharma US, Inc., Deerfield, IL), which is administered twice …
tacrolimus (Prograf, Astellas Pharma US, Inc., Deerfield, IL), which is administered twice …
Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients
LM Andrews, YI Li, BCM De Winter, YY Shi… - Expert opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Tacrolimus (Tac) is the cornerstone of immunosuppressive therapy
after solid organ transplantation and will probably remain so. Excluding belatacept, no new …
after solid organ transplantation and will probably remain so. Excluding belatacept, no new …
TDM is Alive and Kicking!
F Lemaitre, DA Hesselink - Therapeutic Drug Monitoring, 2023 - journals.lww.com
British Journal of Clinical Pharmacology. The authors describe the target concentration
intervention (TCI) concept and oppose it to the principle of therapeutic drug monitoring …
intervention (TCI) concept and oppose it to the principle of therapeutic drug monitoring …
Therapeutic drug monitoring of tacrolimus in clinical transplantation
P McMaster, DF Mirza, T Ismail… - Therapeutic drug …, 1995 - journals.lww.com
Initial clinical trials of FK did not incorporate available FK levels, and difficulties were quickly
experienced particularly with neurotoxicity and nephrotoxicity. The introduction of routine …
experienced particularly with neurotoxicity and nephrotoxicity. The introduction of routine …
Comparison of an ELISA and an LC/MS/MS method for measuring tacrolimus concentrations and making dosage decisions in transplant recipients
This study compared an enzyme-linked immunosorbent assay (ELISA) to a liquid
chromatography–tandem mass spectrometry (LC/MS/MS) technique for measurement of …
chromatography–tandem mass spectrometry (LC/MS/MS) technique for measurement of …
Evaluation of a standardized tacrolimus therapeutic drug monitoring protocol in stable kidney transplant recipients
TQ Ky, NP Silas, RM Taylor… - Progress in …, 2022 - journals.sagepub.com
Introduction: Transplant nurse coordinators have assisted in accurately adjusting tacrolimus
doses under a collaborative practice agreement for kidney transplant recipients in the early …
doses under a collaborative practice agreement for kidney transplant recipients in the early …
Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report
M Brunet, T Van Gelder, A Åsberg… - Therapeutic drug …, 2019 - journals.lww.com
Ten years ago, a consensus report on the optimization of tacrolimus was published in this
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …