Impressive progress has been made over the last several years toward understanding how
almost every aspect of the immune system contributes to the expression of systemic …

Systemic lupus erythematosus (SLE) is a complex polygenic autoimmune disease
characterized by the presence of anti‐nuclear autoantibodies (ANAs) that are often …

Systemic lupus erythematosus (SLE) is an autoimmune disease mediated by pathogenic
autoantibodies directed against nucleoprotein complexes. Beyond the activation of …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with profound effects
on multiple organ systems. In patients with SLE, the immune system is subverted to target …

The origins of autoimmunity in systemic lupus erythematosus (SLE) are thought to involve
both genetic and environmental factors. To identify environmental agents that could …

Recent progress towards elucidating the genetic basis for susceptibility to systemic lupus
erythematosus (SLE) has provided insights into the manner in which individual susceptibility …

Systemic lupus erythematosus (SLE) is inherited as a complex polygenic trait, involving
genetic, environmental and stochastic factors. Although definition of these etiologic …

Patients with systemic lupus erythematosis (SLE) often manifest features of other
autoimmune diseases. In this review, we provide a detailed compendium of features of SLE …

Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-
tolerance with activation of autoreactive T and B cells leading to production of pathogenic …

The aetiology of systemic lupus erythematosus (SLE) is multifactorial, and includes
contributions from the environment, stochastic factors, and genetic susceptibility. Great gains …