The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …

Nanocarriers as drug delivery systems are promising and becoming popular, especially for
cancer treatment. In addition to improving the pharmacokinetics of poorly soluble …

Stem cell-based regenerative medicine holds exceptional therapeutic potential and hence
the development of efficient techniques to enhance control over the rate of differentiation has …

RNA interference is a powerful method for the knockdown of pathologically relevant genes.
Small interfering RNAs (siRNAs) have been widely demonstrated as effective biomedical …

Introduction: siRNA has poor in vivo stability and has a plasma half life of only a few minutes
after intravenous administration. These problems can be overcome by conjugating …

The discovery of RNA interference has revitalized the long ongoing pursuit of gene therapy
for the treatment of diseases. Nevertheless, despite promising results from experimental …

RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …

Background: Despite therapeutics based on siRNA have an immense potential for the
treatment of incurable diseases such as cancers. However, the in vivo utilization of siRNA …

Although numerous formulations are being devised lately, focus should remain on biological
stability, specificity and safety of these nanocarriers, which can be easily translatable from …

Increasing knowledge about molecular mechanisms of endogenous RNA interference
(RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic …