Extensive clinical investigation has shown that ketanserin is an effective first‐line
antihypertensive agent with particular advantages in older patients. It has a favorable …

The possible use of ketanserin for the chronic treatment of patients with essential
hypertension was discussed based on the data exposed at this symposium. Its hypotensive …

Ketanserin is a 5-HT 2 receptor antagonist without partial agonist properties which also
possesses weak α 1-adrenoceptor antagonistic activity, which may explain its …

Ketanserin is a serotonin (S,) Mocker that reduces blood pressure (BP) in patients with
essential hypertension preferentially by a reduction of peripheral vascular resistance. Heart …

Ketanserin is the archetype of a new class of cardiovascular drugs, the 5HT 2 (S 2)
serotonergic receptor antagonists. In humans, ketanserin inhibits serotonin-induced …

Ketanserin is a serotonin antagonist with high affinity for S2-serotonergic receptors, which
mediate the vasoconstrictor effects of serotonin. It does not block the vasodilator effects of …

In the Swiss Ketanserin Study the antihypertensive efficacy and tolerability of ketanserin
(given in 20 or 40 mg doses twice daily) was investigated, after a placebo run-in phase, as …

To assess efficacy and side effects during chronic oral therapy, we studied the effect of
ketanserin (Kn) in 17 hypertensive patients for a period up to 1 year. Ketanserin controlled …

Ketanserin is an agent whose main pharmacologic action is antagonism of serotonin (5-
hydroxytryptamine, 5HT) receptors of the 5HT2 subtype. It also has weak α1-adrenergic …

Ketanserin is a quinazoline derivative which acts selectively on serotonin (S2) receptors.
The compound has been shown to possess antihypertensive properties. BP and HR were …