The release of transmitters at sympathoeffector junctions is not constant, but subject to
modulation by a plethora of different mechanisms. In this respect, presynaptic receptors …

Sympathetic preganglionic neurons (SPN) are critical links in the sympathetic neural circuitry
that controls every organ in the body. All sympathetic outflow to the periphery comes from …

The sympathetic nervous system comprises one half of the autonomic nervous system and
participates in maintaining homeostasis and enabling organisms to respond in an …

Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrenaline were
first described more than three decades ago. Molecular cloning has resulted in the …

Aim: On structural grounds, synaptic transmission in sympathetic ganglia is potentially
complex with extensive divergence and convergence between preganglionic and …

Sympathetic nerve activity (SNA) contributes appreciably to the control of physiological
function, such that pathological alterations in SNA can lead to a variety of diseases. The goal …

With advances in experimental techniques, the early views of the sympathetic nervous
system as a monolithic effector activated globally in situations requiring a rapid and …

Abstract [alpha] 2-Adrenergic agonists produce analgesia and reduce hemodynamic stress
through central and peripheral mechanisms, but the effect of adrenergic agonists on pre-and …

The sympathetic nervous system regulates many different target tissues in the somatic and
visceral domains of the body in a differentiated manner, indicating that there exist separate …

The release of neurotransmitters is modulated through presynaptic autoreceptors that are
acted upon by the neurone's own transmitter. The presynaptic inhibitory terminal …