(Radio) Fluorination Reactions for the Synthesis of Aryl Fluorides: Recent Advances and Perspectives

J Han, Z Zhang - European Journal of Organic Chemistry - Wiley Online Library
The formation of carbon‐fluorine (C‐F) bonds is an important research field in organic
synthesis because the insertion of a fluorine atom into an organic compound can alter its …

Advances in nucleophilic allylic fluorination

AM Sorlin, FO Usman, CK English, HM Nguyen - ACS Catalysis, 2020 - ACS Publications
Numerous procedures focus on inserting the fluorine atom into the carbon frameworks of
synthetically useful target molecules using various nucleophilic fluorinating reagents …

Modern carbon–fluorine bond forming reactions for aryl fluoride synthesis

MG Campbell, T Ritter - Chemical Reviews, 2015 - ACS Publications
In recent years, there has been a dramatic increase in available methods for the installation
of fluorine and fluorine-containing functional groups in organic molecules, 1− 4 and the …

Recent advances in green fluorine chemistry

Y Zeng, J Hu - Reports in Organic Chemistry, 2015 - Taylor & Francis
Fluorinated compounds are intriguing for the development of pharmaceuticals,
agrochemicals, and materials, and thus, much effort has been exerted to develop more …

The unique fluorine effects in organic reactions: recent facts and insights into fluoroalkylations

C Ni, J Hu - Chemical Society Reviews, 2016 - pubs.rsc.org
Fluoroalkylation reaction, featuring the transfer of a fluoroalkyl group to a substrate, is a
straightforward and efficient method for the synthesis of organofluorine compounds. In …

Aromatic fluorination using transition metals

S Yoshida - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic …, 2010 - tus.elsevierpure.com
Despite increasing pharmaceutical importance, fluorinated arenes remain difficult to
synthesize. Particularly, developing general methods that enables to introduce fluoride on …

Where does the fluorine come from? A review on the challenges associated with the synthesis of organofluorine compounds

S Caron - Organic Process Research & Development, 2020 - ACS Publications
Fluorinated organic molecules are increasingly being prepared for a variety of applications,
including pharmaceutical products. However, the supply chain to access the necessary raw …

Activation and formation of aromatic C–F bonds

NA LaBerge, JA Love - Organometallic fluorine chemistry, 2015 - Springer
The presence of aryl C–F bonds in pharmaceuticals and agrochemicals is increasing
rapidly. Incorporation of a fluorine substituent into biologically relevant molecules yields …

[HTML][HTML] Ring-opening fluorination via C–C bond cleavage: An efficient approach to diverse fluorinated molecules

YC Lu, JG West - Tetrahedron Chem, 2022 - Elsevier
The unique and desirable properties of fluorinated compounds in pharmaceutical,
agrochemical, and materials sciences have driven the development of remote fluorination …

Transition metal catalysis and nucleophilic fluorination

C Hollingworth, V Gouverneur - Chemical communications, 2012 - pubs.rsc.org
Transition metal catalyzed transformations using fluorinating reagents have been developed
extensively for the preparation of synthetically valuable fluorinated targets. This is a topic of …