[HTML][HTML] Resolution of deep venous thrombosis: proposed immune paradigms

JM Nicklas, AE Gordon, PK Henke - International Journal of Molecular …, 2020 - mdpi.com
Venous thromboembolism (VTE) is a pathology encompassing deep vein thrombosis (DVT)
and pulmonary embolism (PE) associated with high morbidity and mortality. Because …

Crossroads of coagulation and innate immunity: the case of deep vein thrombosis

C Schulz, B Engelmann… - Journal of thrombosis and …, 2013 - Wiley Online Library
Deep vein thrombosis (DVT) is a common condition characterized by the formation of an
occlusive blood clot in the venous vascular system, potentially complicated by detachment …

[HTML][HTML] Fibrinolysis and inflammation in venous thrombus resolution

S Mukhopadhyay, TA Johnson, N Duru… - Frontiers in …, 2019 - frontiersin.org
Clinical observations and accumulating laboratory evidence support a complex interplay
between coagulation, inflammation, innate immunity and fibrinolysis in venous …

[HTML][HTML] Multiple facets of venous thrombosis

A Brill - International Journal of Molecular Sciences, 2021 - mdpi.com
Venous thromboembolism, a complex disease combining deep vein thrombosis (DVT) and
its most dangerous complication, pulmonary embolism (PE), strikes millions of people …

The role of neovascularisation in the resolution of venous thrombus

B Modarai, KG Burnand, J Humphries… - Thrombosis and …, 2005 - thieme-connect.com
Deep vein thrombosis (DVT) can give rise to chronic debilitating complications, which are
expensive to treat. Anticoagulation, the standard therapy for DVT, prevents propagation, but …

Toll-like receptor 9 signaling is critical for early experimental deep vein thrombosis resolution

PK Henke, M Mitsuya, CE Luke, MA Elfline… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Toll-like receptors (TLR) bridge innate immunity and host responses, including
inflammation. Sterile inflammation such as a venous thrombus (Vt) may involve TLR …

Divergent effects of Tlr9 deletion in experimental late venous thrombosis resolution and vein wall injury

NA Dewyer, OM El-Sayed, CE Luke… - Thrombosis and …, 2015 - thieme-connect.com
Deep-vein thrombosis (DVT) resolves via a sterile inflammatory response. Defining the
inflammatory response of DVT may allow for new therapies that do not involve …

[HTML][HTML] Immune factors in deep vein thrombosis initiation

I Budnik, A Brill - Trends in immunology, 2018 - cell.com
Deep vein thrombosis (DVT) is a major origin of morbidity and mortality. While DVT has long
been considered as blood coagulation disorder, several recent lines of evidence …

Mechanisms of venous thrombosis and resolution

TW Wakefield, DD Myers, PK Henke - … , thrombosis, and vascular …, 2008 - Am Heart Assoc
Venous thromboembolism is a significant health care problem in the US. In this review, the
unique role of inflammation to the venous thrombotic process is emphasized as well as the …

[HTML][HTML] Venous thrombosis and post-thrombotic syndrome: from novel biomarkers to biology

AK Metz, JA Diaz, AT Obi, TW Wakefield… - Methodist DeBakey …, 2018 - ncbi.nlm.nih.gov
Deep vein thrombosis (DVT) is a common disease that carries serious ramifications for
patients, including pulmonary embolism and post-thrombotic syndrome (PTS). Although …