Background Anterior cruciate ligament (ACL) rupture in humans is a common condition
associated with knee pain, joint instability, and secondary osteoarthritis (OA). Surgical …

Anterior cruciate ligament (ACL) tears are a common knee injury with a known but poorly
understood association with secondary joint injuries and post‐traumatic osteoarthritis (OA) …

OBJECTIVE: To identify genes which may be involved in the development of anterior
cruciate ligament (ACL) laxity and rupture in a naturally occurring canine osteoarthritis (OA) …

Large animal (non-rodent mammal) models are commonly used in ACL research, but no
species is currently considered the gold standard. Important considerations when selecting …

ACL tears are significant knee injuries that can have detrimental long-term consequences
and result in significant health care costs. Although ligament reconstruction is currently the …

Anterior cruciate ligament (ACL) injuries are common knee ligament injuries. While
generally successful, ACL reconstruction that uses a tendon graft to stabilize the knee is still …

Reconstruction of the anterior cruciate ligament (ACL) is a common surgical procedure with
an estimated 50,000 procedures in the US annually. Injury of the ACL often requires costly …

A major hurdle in investigating important clinical questions in knee ligament treatment is a
lack of valid translational animal models. This study characterizes the effects of partial …

Transection of the canine anterior cruciate ligament (ACL) is a well‐established
osteoarthritis (OA) model. This study evaluated a new method of canine ACL disruption as …

Small animal models are critical for studies of sports-related knee injury and disease such
as posttraumatic osteoarthritis (PTOA) following anterior cruciate ligament (ACL) rupture. In …