Structural chemistry and molecular-level interactome reveals histidine kinase EvgS to subvert both antimicrobial resistance and virulence in Shigella flexneri 2a str …
Multi-drug resistant (MDR) Shigella flexneri 2a, one of the leading bacterial agents of
diarrhoeal mortality, has posed challenges in treatment strategies. The present study was …
diarrhoeal mortality, has posed challenges in treatment strategies. The present study was …
Genome‐Wide Investigation Reveals Potential Therapeutic Targets in Shigella spp.
Shigella stands as a major contributor to bacterial dysentery worldwide scale, particularly in
developing countries with inadequate sanitation and hygiene. The emergence of multidrug …
developing countries with inadequate sanitation and hygiene. The emergence of multidrug …
Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and molecular …
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
Finding Potential Therapeutic Targets against Shigella flexneri through Proteome Exploration
Background: Shigella flexneri is a gram negative bacteria that causes the infectious disease
“shigellosis.” S. flexneri is responsible for developing diarrhea, fever, and stomach cramps in …
“shigellosis.” S. flexneri is responsible for developing diarrhea, fever, and stomach cramps in …
[HTML][HTML] Identification of therapeutic drug target of Shigella Flexneri serotype X through subtractive genomic approach and in-silico screening based on drug …
MH Ahmed, K Khan, S Tauseef, K Jalal… - Infection, Genetics and …, 2024 - Elsevier
Shigellosis, induced by Shigella flexneri, constitutes a significant health burden in
developing nations, particularly impacting socioeconomically disadvantaged communities …
developing nations, particularly impacting socioeconomically disadvantaged communities …
[HTML][HTML] Shigella pathogenesis: molecular and computational insights
S Mukhopadhyay, S Ganguli… - AIMS Molecular …, 2020 - aimspress.com
Shigellosis, characterized by inflammation and ulceration of the large intestine, is caused by
infection with Shigella species. It is a major public health problem in developing countries …
infection with Shigella species. It is a major public health problem in developing countries …
Identification of potential drug targets and inhibitor of the pathogenic bacteria Shigella flexneri 2a through the subtractive genomic approach
Shigella flexneri 2a is one of the most pathogenic bacteria among the Shigella spp., which is
responsible for dysentery and causes masses of deaths throughout the world per year. A …
responsible for dysentery and causes masses of deaths throughout the world per year. A …
[HTML][HTML] An in silico hierarchal approach for drug candidate mining and validation of natural product inhibitors against pyrimidine biosynthesis enzyme in the antibiotic …
Z Basharat, K Khan, K Jalal, D Ahmad, A Hayat… - Infection, Genetics and …, 2022 - Elsevier
Shigella flexneri is the main causative agent of the communicable diarrheal disease,
shigellosis. It is estimated that about 80–165 million cases and> 1 million deaths occur every …
shigellosis. It is estimated that about 80–165 million cases and> 1 million deaths occur every …
In Silico Characterization of a Hypothetical Protein from Shigella dysenteriae ATCC 12039 Reveals a Pathogenesis-Related Protein of the Type-VI Secretion System
Shigellosis caused by Shigella dysenteriae is a major public health concern worldwide,
particularly in developing countries. The bacterial genome is known, but there are many …
particularly in developing countries. The bacterial genome is known, but there are many …
iTRAQ-Based Differential Proteomic Analysis Reveals the Pathways Associated with Tigecycline Resistance in Acinetobacter baumannii
N Yang, Y Liu, P He, R Ke, Y Zhao, Y Feng… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Acinetobacter baumannii is an aerobic and Gram-negative
bacterial pathogen with high morbidity and mortality. It remains a serious public health …
bacterial pathogen with high morbidity and mortality. It remains a serious public health …