Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques
NM Htun, YC Chen, B Lim, T Schiller… - Nature …, 2017 - nature.com
Atherosclerosis is a major cause of mortality and morbidity, which is mainly driven by
complications such as myocardial infarction and stroke. These complications are caused by …
complications such as myocardial infarction and stroke. These complications are caused by …
Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques
MA Calfon, C Vinegoni… - Journal of biomedical …, 2010 - spiedigitallibrary.org
New imaging methods are urgently needed to identify high-risk atherosclerotic lesions prior
to the onset of myocardial infarction, stroke, and ischemic limbs. Molecular imaging offers a …
to the onset of myocardial infarction, stroke, and ischemic limbs. Molecular imaging offers a …
Label-free visualization and quantification of biochemical markers of atherosclerotic plaque progression using intravascular fluorescence lifetime
Objectives This study aimed to systematically investigate whether plaque autofluorescence
properties assessed with intravascular fluorescence lifetime imaging (FLIm) can provide …
properties assessed with intravascular fluorescence lifetime imaging (FLIm) can provide …
Clinical characterization of coronary atherosclerosis with dual-modality OCT and near-infrared autofluorescence imaging
GJ Ughi, H Wang, E Gerbaud, JA Gardecki… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The authors present the clinical imaging of human coronary arteries in vivo using
a multimodality optical coherence tomography (OCT) and near-infrared autofluorescence …
a multimodality optical coherence tomography (OCT) and near-infrared autofluorescence …
Near-infrared spectroscopic characterization of human advanced atherosclerotic plaques
Objectives: Living human carotid atherosclerotic plaques were examined in vitro by near-
infrared (NIR) spectroscopy to determine the spectral features of plaque vulnerability …
infrared (NIR) spectroscopy to determine the spectral features of plaque vulnerability …
Intravascular molecular imaging: near-infrared fluorescence as a new frontier
H Khraishah, FA Jaffer - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
Despite exciting advances in structural intravascular imaging [intravascular ultrasound
(IVUS) and optical coherence tomography (OCT)] that have enabled partial assessment of …
(IVUS) and optical coherence tomography (OCT)] that have enabled partial assessment of …
Multimodal characterization of compositional, structural and functional features of human atherosclerotic plaques
Y Sun, AJ Chaudhari, M Lam, H Xie… - Biomedical optics …, 2011 - opg.optica.org
Detection of atherosclerotic plaque vulnerability has critical clinical implications for avoiding
sudden death in patients with high risk of plaque rupture. We report on multimodality …
sudden death in patients with high risk of plaque rupture. We report on multimodality …
In vivo near infrared fluorescence (NIRF) intravascular molecular imaging of inflammatory plaque, a multimodal approach to imaging of atherosclerosis
MA Calfon, A Rosenthal, G Mallas, A Mauskapf… - JoVE (Journal of …, 2011 - jove.com
The vascular response to injury is a well-orchestrated inflammatory response triggered by
the accumulation of macrophages within the vessel wall leading to an accumulation of lipid …
the accumulation of macrophages within the vessel wall leading to an accumulation of lipid …
Hyperspectral imaging of atherosclerotic plaques in vitro
ELP Larsen, LL Randeberg, E Olstad… - … of biomedical optics, 2011 - spiedigitallibrary.org
Vulnerable plaques constitute a risk for serious heart problems, and are difficult to identify
using existing methods. Hyperspectral imaging combines spectral-and spatial information …
using existing methods. Hyperspectral imaging combines spectral-and spatial information …
Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques
Y Narita, K Shimizu, K Ikemoto, R Uchino… - Journal of Controlled …, 2019 - Elsevier
The development of atherosclerotic plaques is a critical step that can result in an arterial
embolism. Therefore, detection of these vulnerable plaques is of clinical significance for the …
embolism. Therefore, detection of these vulnerable plaques is of clinical significance for the …