Molecular mechanisms of the anti-cancer effects of isothiocyanates from cruciferous vegetables in bladder cancer

T Mastuo, Y Miyata, T Yuno, Y Mukae, A Otsubo… - Molecules, 2020 - mdpi.com
Bladder cancer (BC) is a representative of urological cancer with a high recurrence and
metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint …

Inhibition of bladder cancer development by allyl isothiocyanate

A Bhattacharya, L Tang, Y Li, F Geng… - …, 2010 - academic.oup.com
Bladder cancer is one of the common human cancers and also has a very high recurrence
rate. There is a great need for agents capable of inhibiting bladder cancer development and …

Mechanisms of the anticancer effects of isothiocyanates

NM Fofaria, A Ranjan, SH Kim, SK Srivastava - The enzymes, 2015 - Elsevier
Cancer results from aberrant signaling pathways that result in uncontrolled cellular
proliferation. The epidemiological studies have shown a strong inverse correlation between …

Effects of Brassicaceae Isothiocyanates on Prostate Cancer

S Novío, ME Cartea, P Soengas, M Freire-Garabal… - Molecules, 2016 - mdpi.com
Despite the major progress made in the field of cancer biology, cancer is still one of the
leading causes of mortality, and prostate cancer (PCa) is one of the most encountered …

Isothiocyanates in the chemoprevention of bladder cancer

L Tang, Y Zhang - Current drug metabolism, 2004 - ingentaconnect.com
Development of effective preventive strategies for bladder cancer is of critical importance.
Bladder cancer is among the most common human malignancies and typically recurs after …

Allyl isothiocyanate as a cancer chemopreventive phytochemical

Y Zhang - Molecular nutrition & food research, 2010 - Wiley Online Library
Allyl isothiocyanate (AITC), which occurs in many common cruciferous vegetables, is widely
and often frequently consumed by humans. Besides antimicrobial activity against a wide …

The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in …

L Tang, G Li, L Song, Y Zhang - Anti-cancer drugs, 2006 - journals.lww.com
Isothiocyanates (ITCs) are a class of well-known cancerpreventive phytochemicals, but are
primarily disposed of and concentrated in the urine as N-acetylcysteine conjugates (NAC …

Molecular targets of isothiocyanates in cancer: recent advances

P Gupta, B Kim, SH Kim… - Molecular nutrition & food …, 2014 - Wiley Online Library
Cancer is a multistep process resulting in uncontrolled cell division. It results from aberrant
signaling pathways that lead to uninhibited cell division and growth. Various recent …

Are isothiocyanates potential anti-cancer drugs?

X Wu, Q Zhou, K Xu - Acta Pharmacologica Sinica, 2009 - nature.com
Isothiocyanates are naturally occurring small molecules that are formed from glucosinolate
precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic …

Effect of sulforaphane on cell growth, G0/G1 phase cell progression and apoptosis in human bladder cancer T24 cells

Y Shan, C Sun, X Zhao, K Wu… - … journal of oncology, 2006 - spandidos-publications.com
Isothiocyanates (ITCs) from cruciferous vegetables have been shown to be effective in
blocking initiation as well as progression of a range of chemically-induced tumors in animal …