Toehold-mediated strand displacement (TMSD) reactions between double-stranded DNA
and single-stranded oligonucleotides, which use a toehold structure as a switch, enable …

Toehold-mediated DNA strand displacement has proven powerful in the construction of
various DNA circuits, DNA machines, and biosensors. So far, many new toehold activation …

Background The DNA strand displacement reaction, which uses flexible and programmable
DNA molecules as reaction components, is the basis of dynamic DNA nanotechnology, and …

DNA has many unique properties beyond encoding genetic information, one of which is its
physicochemical stability based on Watson–Crick base pairing. Differences in sequence …

Toehold-mediated DNA strand displacement provides unique advantages in the
construction and manipulation of multidimensional DNA nanostructures as well as nucleic …

The enzyme-free toehold-mediated strand displacement reaction has shown potential for
building programmable DNA circuits, biosensors, molecular machines and chemical …

Toehold-mediated strand displacement (TMSD) is widely employed in constructing a wide
range of chemical reaction networks. In TMSD, single-stranded DNA or RNA can fold back …

Strand exchange between homologous nucleic acid sequences is the basis for cellular DNA
repair, recombination, and genome editing technologies. Specialized enzymes catalyze …

SemiSynBio is an emerging topic toward the construction of platforms for next-generation
information processing. Recent research has indicated its promising prospect toward …

DNA is increasingly being used as the engineering material of choice for the construction of
nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function …