Kidney organoids generated from induced pluripotent stem cells (iPSC) have proven
valuable for studies of kidney development, disease, and therapeutic screening. However …

In the past five years, pluripotent stem cell (PSC)-derived kidney organoids and adult stem
or progenitor cell (ASC)-based kidney tubuloids have emerged as advanced in vitro models …

Maximizing the potential of human kidney organoids for drug testing and regenerative
medicine and to model development and disease requires addressing cell immaturity, the …

Kidney organoids derived from human induced pluripotent stem cells bear the potential to
be used as a regenerative medicine renal replacement therapy. Advances in developmental …

Background The generation of reporter lines for cell identity, lineage, and physiologic state
has provided a powerful tool in advancing the dissection of mouse kidney morphogenesis at …

Kidney organoids can be generated from human pluripotent stem cells (PSCs) using
protocols that resemble the embryonic development of the kidney. The renal structures thus …

Directed differentiation of human pluripotent stem cells (hPSCs) into functional ureteric and
collecting duct (CD) epithelia is essential to kidney regenerative medicine. Here we describe …

Organoids are self-organizing, multicellular structures that contain multiple cell types,
represent organ structure and function, and can be used to model organ development …

Protocols have been established to direct the differentiation of human induced pluripotent
stem (iPS) cells into nephron progenitor cells and organoids containing many types of …

Directed differentiation of human pluripotent stem cells (hPSCs) can provide us any required
tissue/cell types by recapitulating the development in vitro. The kidney is one of the most …