[HTML][HTML] Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis
SH Shah, NJ Freedman, L Zhang, DR Crosslin… - PLoS …, 2009 - journals.plos.org
Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We
have previously identified genetic linkage to familial CAD in the genomic region of NPY. We …
have previously identified genetic linkage to familial CAD in the genomic region of NPY. We …
Of mice and men: neuropeptide Y and its receptors are associated with atherosclerotic lesion burden and vulnerability
L Li, AH Najafi, JB Kitlinska, R Neville, J Laredo… - Journal of …, 2011 - Springer
Neuropeptide Y (NPY), a sympathetic and platelet-derived vascular mitogen and angiogenic
factor, has been implicated in atherosclerosis in animal and human genetic studies. Here we …
factor, has been implicated in atherosclerosis in animal and human genetic studies. Here we …
Association analysis of the polymorphism T1128C in the signal peptide of neuropeptide Y in a Swedish hypertensive population
SM Wallerstedt, S Skrtic, AL Eriksson… - Journal of …, 2004 - journals.lww.com
Objective The neuropeptide Y (NPY) signal peptide polymorphism T1128C has been linked
to several risk factors for cardiovascular disease. The aim of the present study was to …
to several risk factors for cardiovascular disease. The aim of the present study was to …
Enhanced endothelium-dependent vasodilation in subjects with Proline7 substitution in the signal peptide of neuropeptide Y
MJ Järvisalo, L Jartti, MK Karvonen, U Pesonen… - Atherosclerosis, 2003 - Elsevier
Neuropeptide Y (NPY) is a molecule that may have both vasoconstrictive and vasodilatory
actions. A common polymorphism in the human NPY gene that results in the Leucine7 to …
actions. A common polymorphism in the human NPY gene that results in the Leucine7 to …
The role of neuropeptide Y in the pathophysiology of atherosclerotic cardiovascular disease
P Zhu, W Sun, C Zhang, Z Song, S Lin - International journal of cardiology, 2016 - Elsevier
With average life expectancy rising greatly, the incidence rate of arteriosclerotic
cardiovascular disease (ASCVD) has significantly increased. The heart disease has now …
cardiovascular disease (ASCVD) has significantly increased. The heart disease has now …
Vascular neuropeptide Y contributes to atherosclerotic plaque progression and perivascular mast cell activation
HM Lagraauw, MM Westra, M Bot, A Wezel… - Atherosclerosis, 2014 - Elsevier
Aim Neuropeptide Y is an abundantly expressed neurotransmitter capable of modulating
both immune and metabolic responses related to the development of atherosclerosis. NPY …
both immune and metabolic responses related to the development of atherosclerosis. NPY …
Association of leucine 7 to proline 7 polymorphism in the preproneuropeptide Y with serum lipids in patients with coronary heart disease
AT Erkkilä, V Lindi, S Lehto, M Laakso… - Molecular genetics and …, 2002 - Elsevier
Leucine 7 (Leu7) to proline 7 (Pro7) substitution in the neuropeptide Y (NPY) gene has been
associated with higher serum total and low-density lipoprotein (LDL) cholesterol levels …
associated with higher serum total and low-density lipoprotein (LDL) cholesterol levels …
Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and …
L Niskanen, MK Karvonen, R Valve… - The Journal of …, 2000 - academic.oup.com
We have recently demonstrated that subjects having Pro7 in the signal peptide of
neuropeptide Y (NPY) have higher serum cholesterol and apolipoprotein B levels than …
neuropeptide Y (NPY) have higher serum cholesterol and apolipoprotein B levels than …
Systemic treatment with neuropeptide Y receptor Y1-antagonist enhances atherosclerosis and stimulates IL-12 expression in ApoE deficient mice
AE Jääskeläinen, S Seppälä, T Kakko, U Jaakkola… - Neuropeptides, 2013 - Elsevier
AIMS: Neuropeptide Y (NPY) and Y1 receptors are involved in the mechanisms related to
the development of atherosclerosis. We investigated the effects of systemically given NPY …
the development of atherosclerosis. We investigated the effects of systemically given NPY …
Neuropeptide Y gene variants in obesity, dietary intake, blood pressure, lipid and glucose metabolism: A longitudinal birth cohort study
U Katus, I Villa, I Ringmets, T Veidebaum, J Harro - Peptides, 2021 - Elsevier
Objective Neuropeptide Y affects several physiological functions, notably appetite
regulation. We analysed the association between four single nucleotide polymorphisms …
regulation. We analysed the association between four single nucleotide polymorphisms …