Pharmacological approaches to pulmonary fibrosis following COVID-19

S Lassan, T Tesar, J Tisonova… - Frontiers in …, 2023 - frontiersin.org
Background: In the past few years, COVID-19 became the leading cause of morbidity and
mortality worldwide. Although the World Health Organization has declared an end to COVID …

Lung fibrosis: Post-COVID-19 complications and evidences

R Hirawat, N Jain, MA Saifi, M Rachamalla… - International …, 2023 - Elsevier
Background COVID 19, a lethal viral outbreak that devastated lives and the economy across
the globe witnessed non-compensable respiratory illnesses in patients. As been evaluated …

Lung fibrosis after COVID-19: treatment prospects

E Bazdyrev, P Rusina, M Panova, F Novikov… - Pharmaceuticals, 2021 - mdpi.com
At the end of 2019, a highly contagious infection began its ominous conquest of the world. It
was soon discovered that the disease was caused by a novel coronavirus designated as …

The interaction between pulmonary fibrosis and COVID-19 and the application of related anti-fibrotic drugs

H Shen, N Zhang, Y Liu, X Yang, Y He, Q Li… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is a highly contagious respiratory disease, which mainly affects the lungs.
Critically ill patients are easily complicated by cytokine storms, acute respiratory distress …

Pulmonary fibrosis from molecular mechanisms to therapeutic interventions: lessons from post-COVID-19 patients

C Giacomelli, R Piccarducci, L Marchetti… - Biochemical …, 2021 - Elsevier
Pulmonary fibrosis (PF) is characterised by several grades of chronic inflammation and
collagen deposition in the interalveolar space and is a hallmark of interstitial lung diseases …

Pulmonary fibrosis in COVID-19: mechanisms, consequences and targets

S O'Reilly - QJM: An International Journal of Medicine, 2023 - academic.oup.com
Pulmonary fibrosis is characterized by extracellular deposition in the lung primarily collagen
but also other ECM molecules. The primary cell type responsible for this is the myofibroblast …

Common molecular pathways between post-COVID19 syndrome and lung fibrosis: a scoping review

L Bergantini, A Mainardi, M d'Alessandro… - Frontiers in …, 2022 - frontiersin.org
The pathogenetic mechanism of post-Covid-19 pulmonary fibrosis is currently a topic of
intense research interest, but still largely unexplored. The aim of this work was to carry out a …

COVID-19 and pulmonary fibrosis: therapeutics in clinical trials, repurposing, and potential development

J Yim, HH Lim, Y Kwon - Archives of pharmacal research, 2021 - Springer
In 2019, an unprecedented disease named coronavirus disease 2019 (COVID-19) emerged
and spread across the globe. Although the rapid transmission of COVID-19 has resulted in …

Post-COVID-19 pulmonary fibrosis: an update

N Kumar, A Gupta, H Vardhan… - … in Medicine (E …, 2021 - medical …
Abstract Coronavirus disease 2019 (COVID-19) is caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The most common cause of …

COVID-related fibrosis: insights into potential drug targets

G Sgalla, A Comes, M Lerede… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Lung injury in severe COVID-19 pneumonia can rapidly evolve to established
pulmonary fibrosis, with prognostic implications in the acute phase of the disease and long …