Scarce research into the secondary metabolites of the fungi Pseudogymnoascus spp. has
shown a hidden biosynthetic potential for biologically active compounds. This work …

The fungal strains Pseudogymnoascus are a kind of psychrophilic pathogenic fungi that are
ubiquitously distributed in Antarctica, while the studies of their secondary metabolites are …

Strategies for reducing inflammation in neurodegenerative diseases have attracted
increasing attention. Herein, we discovered and evaluated the neuroprotective potential of …

A synthetic biology approach based on genome mining and heterologous biosynthesis is a
powerful tool for discovering novel natural products from a tremendous gene resource. We …

With the advancement of bioinformatics, the integration of genome mining with efficient
separation technology enables the discovery of a greater number of novel bioactive …

The species Pseudogymnoascus is known as a psychrophilic pathogenic fungus with a
ubiquitous distribution in Antarctica. Meanwhile, the study of its secondary metabolites is …

Due to a rate increase in the resistance of microbial pathogens to currently used antibiotics,
there is a need in society for the discovery of novel antimicrobials. Historically, fungi are a …

Microsphaeropsis, taxonomically classified within the kingdom fungi, phylum Ascomycota,
subphylum Deuteromycotina, class Coelomycetes, order Sphaeropsidales, and family …

Streptomyces sp. strain 150FB, isolated from the cap surface of a bolete mushroom, inhibits
the growth of the mycoparasitic Sepedonium species. Functional annotation of the strain …

The fungus, Tritirachium sp. HKI 0317, was isolated from the Antarctic lichen Neuropogon
sp. Fermentation of this strain, extraction of the culture broth, and preparative separation of …