Glypicans are evolutionary conserved, cell surface heparan sulfate (HS) proteoglycans that
are attached to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor …

Glypicans are a family of heparan sulfate proteoglycans that are attached to the cell
membrane via a glycosylphosphatidylinositol anchor. Glypicans interact with multiple …

Glypicans are a group of cell-surface glycoproteins in which heparan sulfate (HS)
glycosaminoglycan chains are covalently linked to a protein core. The glypican gene family …

Abstract Glypican-1 (GPC-1) is a cell surface heparan sulphate proteoglycan that is critical
during normal development, but which is not required for normal homoeostasis in the adult …

Glioblastoma is one of the most common malignant brain tumors, with which patients have a
mean survival of 24 months. Glypican-1 has been previously shown to be overexpressed in …

Signaling peptides of the extracellular environment regulate cell biological processes
underlying embryonic development, tissue homeostasis, and pathophysiology. The heparan …

Glypicans are a family of glycosylphosphatidylinositol-anchored cell surface heparan sulfate
proteoglycans implicated in the control of cellular growth and differentiation. Here we show …

Hepatocellular carcinoma (HCC) remains a common malignant cancer worldwide. There is
an urgent need to identify new molecular targets for the development of novel therapeutic …

Glypican-1 (GPC-1) and other glypicans are a family of heparan sulfate proteoglycans.
These proteins are highly expressed on the cell membrane and in the extracellular matrix …

Purpose Treatment of metastatic breast cancer patients is challenging and remains a major
underlying cause of female mortality. Understanding molecular alterations in tumor …