Assessment of neuroanatomical endophenotypes of autism spectrum disorder and association with characteristics of individuals with schizophrenia and the general …
G Hwang, J Wen, S Sotardi, ES Brodkin… - JAMA …, 2023 - jamanetwork.com
Importance Autism spectrum disorder (ASD) is associated with significant clinical,
neuroanatomical, and genetic heterogeneity that limits precision diagnostics and treatment …
neuroanatomical, and genetic heterogeneity that limits precision diagnostics and treatment …
Dissecting autism and schizophrenia through neuroimaging genomics
Neuroimaging genomic studies of autism spectrum disorder and schizophrenia have mainly
adopted a 'top-down'approach, beginning with the behavioural diagnosis, and moving down …
adopted a 'top-down'approach, beginning with the behavioural diagnosis, and moving down …
[HTML][HTML] Common and unique multimodal covarying patterns in autism spectrum disorder subtypes
Background The heterogeneity inherent in autism spectrum disorder (ASD) presents a
substantial challenge to diagnosis and precision treatment. Heterogeneity across biological …
substantial challenge to diagnosis and precision treatment. Heterogeneity across biological …
Overlap between autism and schizophrenia: History and current status
M Fitzgerald - Advances in Mental Health and Intellectual Disabilities, 2013 - emerald.com
Purpose–Considerable confusion surrounds the overlapping of autism and schizophrenia.
This has significant implications for clinicians given that correct diagnosis is critical for …
This has significant implications for clinicians given that correct diagnosis is critical for …
[HTML][HTML] Transdiagnostic symptom subtypes across autism spectrum disorders and attention deficit hyperactivity disorder: validated by measures of neurocognition and …
M Zhang, Y Huang, J Jiao, D Yuan, X Hu, P Yang… - BMC psychiatry, 2022 - Springer
Backgrounds Autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder
(ADHD) are neurodevelopmental disorders that exhibit within-disorder heterogeneity and …
(ADHD) are neurodevelopmental disorders that exhibit within-disorder heterogeneity and …
[HTML][HTML] Diagnosis-informed connectivity subtyping discovers subgroups of autism with reproducible symptom profiles
Clinical heterogeneity has been one of the main barriers to develop effective biomarkers
and therapeutic strategies in autism spectrum disorder (ASD). Recognizing this challenge …
and therapeutic strategies in autism spectrum disorder (ASD). Recognizing this challenge …
Robust, generalizable, and interpretable artificial intelligence–derived brain fingerprints of autism and social communication symptom severity
Background Autism spectrum disorder (ASD) is among the most pervasive
neurodevelopmental disorders, yet the neurobiology of ASD is still poorly understood …
neurodevelopmental disorders, yet the neurobiology of ASD is still poorly understood …
Mapping the heterogeneous brain structural phenotype of autism spectrum disorder using the normative model
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder
characterized by substantial clinical and biological heterogeneity. Quantitative and …
characterized by substantial clinical and biological heterogeneity. Quantitative and …
[HTML][HTML] A critical role of brain network architecture in a continuum model of autism spectrum disorders spanning from healthy individuals with genetic liability to …
Studies have shown cortical alterations in individuals with autism spectrum disorders (ASD)
as well as in individuals with high polygenic risk for ASD. An important addition to the study …
as well as in individuals with high polygenic risk for ASD. An important addition to the study …
[HTML][HTML] Reconciling dimensional and categorical models of autism heterogeneity: a brain connectomics and behavioral study
Background Heterogeneity in autism spectrum disorder (ASD) has hindered the
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide …
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide …