Pharmacokinetic properties of trifolirhizin,(–)-maackiain,(–)-sophoranone and 2-(2, 4-dihydroxyphenyl)-5, 6-methylenedioxybenzofuran after intravenous and oral …

SM Jang, SH Bae, WK Choi, JB Park, D Kim, JS Min… - Xenobiotica, 2015 - Taylor & Francis
SKI3301, a standardized dried 50% ethanolic extracts of Sophora tonkinensis, contains four
marker compounds (trifolirhizin, TF;(–)-maackiain, Maack;(–)-sophoranone, SPN, and (2-(2 …

Simultaneous determination of trifolirhizin, (–)‐maackiain, (–)‐sophoranone, and 2‐(2,4‐dihydroxyphenyl)‐5,6‐methylenedioxybenzofuran from Sophora tonkinensis …

H Yoo, KH Ryu, SK Bae, J Kim - Journal of separation science, 2014 - Wiley Online Library
A new liquid chromatography with tandem mass spectrometry method was developed and
validated for the simultaneous determination of trifolirhizin,(–)‐maackiain,(–)‐sophoranone …

SKI3301, a purified herbal extract from Sophora tonkinensis, inhibited airway inflammation and bronchospasm in allergic asthma animal models in vivo

H Yoo, M Kang, S Pyo, HS Chae, KH Ryu, J Kim… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacological relevance Sophora tonkinensis (Leguminosae, ST) is a
traditional herbal plant in Korea and China. Its roots and rhizomes have been used to …

Determination of sophoraflavanone G and kurarinone in rat plasma by UHPLC–MS/MS and its application to a pharmacokinetic study

Z Yang, W Zhang, X Li, B Shan, J Liu… - Journal of separation …, 2016 - Wiley Online Library
This study aimed to develop and validate a simple and sensitive ultra high performance
liquid chromatography tandem mass spectrometry method for the simultaneous …

[HTML][HTML] Sophoricoside from Sophora japonica ameliorates allergic asthma by preventing mast cell activation and CD4+ T cell differentiation in ovalbumin-induced …

BH Kim, S Lee - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Asthma is a chronic inflammatory lung disorder with continuously increasing prevalence
worldwide. Novel strategies are needed to prevent or improve asthma. The aim of this study …

Systematic analysis of chemical profiles of Sophorae tonkinensis Radix et Rhizoma in vitro and in vivo using UPLC‐Q‐TOF‐MSE

W Yuan, Z Huang, S Xiao, Y Zhang… - Biomedical …, 2022 - Wiley Online Library
Abstract Sophorae tonkinensis Radix et Rhizoma (S. tonkinensis) has been recorded as a
'poisonous' Chinese herbal medicine in Chinese Pharmacopoeia 2020. The clinical reaction …

Study on the chemical constituents of Sophora flavescens Ait

L Dan, Z Haijun, G Huiyuan, W Lijun - Shenyang yao ke da xue xue …, 2004 - europepmc.org
Five compounds were isolated by the silica gel column chromatography, and identified by
the physico-chemical characters and many kinds of spectroscopic analyses. Two …

Effects of Animal Strain, Dose, and Cotreatment with Saikosaponin b2 on the Pharmacokinetics of Saikosaponin a in Rats

R Fu, J Liu, Y Xue, Z Zhang, R Song - European journal of drug …, 2019 - Springer
Abstract Background and Objectives Radix Bupleuri (RB, Chaihu in Chinese) has been
used as a traditional medicine for more than 2000 years in China, Japan, Korea, and other …

Pharmacokinetic study of matrine, oxymatrine and oxysophocarpine in rat plasma after oral administration of Sophora flavescens Ait. extract by liquid chromatography …

L Zhang, W Liu, R Zhang, Z Wang, Z Shen… - … of pharmaceutical and …, 2008 - Elsevier
A rapid, sensitive and selective high-performance liquid chromatography tandem mass
spectrometric method (HPLC-MS) has been developed and validated for the simultaneous …

HPLC determination of contents of four flavonoids in different samples of Sophora flavescens Ait. in the market

C XU, L Zhu, B Liu, R Shi - Traditional Chinese Drug …, 1993 - pesquisa.bvsalud.org
Objective To determine the contents of four fiavonoids (trifolirhizin, nor-kurarinone,
xanthonumal and kuraridin) in 25 samples of Sophora flavescens Air. in the market. Methods …