The treatment of onychomycosis remains problematic even though there are several potent
antifungal agents available for patient use. The aim of this investigation was to understand …

Onychomycosis, or fungal nail infection, is a common fungal infection largely caused by
dermatophyte fungi, such as Trichophyton rubrum or Trichophyton mentagrophytes, which …

Background: Onychomycosis is by far the most common finger or toe nail fungal infectious
disease caused by dermatophytes, non-dermatophytic molds or yeast. It accounts for 50% of …

The route of antifungal drug entry into the nail plate and the underlying nail bed plays an
important role in determining the efficacy of therapy. Oral antifungal agents reach the nail …

Onychomycosis is caused by dermatophytes, non‐dermatophytes and yeasts. It has a global
prevalence of 5.5%, requires long treatment periods, and has high relapse rates following …

The impact of hydration on the permeation of the antifungal drug, ketoconazole, through
excised human nails in vitro was evaluated in diffusion cell studies. Nails treated with [3H] …

Onychomycosis is difficult to treat topically due to the deep location of the infection under the
densely keratinized nail plate. In order to obtain an in vitro index that is relevant to the …

Purpose Through the characterisation of the human onchomycotic nail plate this study
aimed to inform the design of new topical ungual formulations. Methods The mechanical …

Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the
deep location of the infection under the densely keratinized nail plate. Keratin affinity of …

Onychomycosis is one of the most common nail disorders. It affects 10− 30% of the world
population and is caused by dermatophytes, non-dermatophytes, molds, and yeasts …