Piperacillin-tazobactam compared with cefoxitin as antimicrobial prophylaxis for pancreatoduodenectomy: a randomized clinical trial

MI D'Angelica, RJ Ellis, JB Liu, BC Brajcich, M Gönen… - Jama, 2023 - jamanetwork.com
Importance Despite improvements in perioperative mortality, the incidence of postoperative
surgical site infection (SSI) remains high after pancreatoduodenectomy. The effect of broad …

Antibiotic prophylaxis with piperacillin–tazobactam reduces post-operative infectious complication after pancreatic surgery: An interventional, non-randomized study

M De Pastena, S Paiella, AM Azzini, A Zaffagnini… - Surgical …, 2021 - liebertpub.com
Background: This study aimed to evaluate the effectiveness of piperacillin–tazobactam as
antibiotic prophylaxis in patients affected by a peri-ampullary tumor submitted to pancreatic …

Discordance between perioperative antibiotic prophylaxis and wound infection cultures in patients undergoing pancreaticoduodenectomy

ZV Fong, MT McMillan, G Marchegiani, K Sahora… - JAMA …, 2016 - jamanetwork.com
Importance Wound infections after pancreaticoduodenectomy (PD) are common. The
standard antibiotic prophylaxis given to prevent the infections is often a cephalosporin …

Perioperative antibiotics for surgical site infection in pancreaticoduodenectomy: does the SCIP-approved regimen provide adequate coverage?

GW Donald, D Sunjaya, X Lu, F Chen, B Clerkin, G Eibl… - Surgery, 2013 - Elsevier
Introduction The Joint Commission Surgical Care Improvement Project (SCIP) includes
performance measures aimed at reducing surgical site infections (SSI). One measure …

Association between biliary pathogens, surgical site infection, and pancreatic fistula: results of a randomized trial of perioperative antibiotic prophylaxis in patients …

RJ Ellis, BC Brajcich, KA Bertens, CHF Chan… - Annals of …, 2023 - journals.lww.com
Objective: To establish the association between bactibilia and postoperative complications
when stratified by perioperative antibiotic prophylaxis. Background: Patients undergoing …

Third-generation cephalosporin for antimicrobial prophylaxis in pancreatoduodenectomy in patients with internal preoperative biliary drainage

S Sano, T Sugiura, I Kawamura, Y Okamura, T Ito… - Surgery, 2019 - Elsevier
Background The aim of the present study was to investigate whether the incidence of
surgical site infection after pancreatoduodenectomy decreased after changing the …

Perioperative antibiotherapy should replace prophylactic antibiotics in patients undergoing pancreaticoduodenectomy preceded by preoperative biliary drainage

O Degrandi, E Buscail, S Martellotto… - Journal of Surgical …, 2019 - Wiley Online Library
Background and objectives Pancreaticoduodenectomy (PD) remains a morbid surgery.
Preoperative biliary drainage (PBD) is often necessary before surgery but is associated with …

[HTML][HTML] A novel, validated risk score to predict surgical site infection after pancreaticoduodenectomy

KE Poruk, JA Lin, MA Cooper, J He, MA Makary… - HPB, 2016 - Elsevier
Background Although pancreaticoduodenectomy (PD) outcomes have improved,
complications including surgical site infection (SSI) remain common. We present a …

Selection of prophylactic antibiotics according to the microorganisms isolated from surgical site infections (SSIs) in a previous series of surgeries reduces SSI …

K Kondo, K Chijiiwa, J Ohuchida, M Kai… - Journal of Hepato …, 2013 - Wiley Online Library
Background The incidence of surgical site infections (SSIs) is high after
pancreaticoduodenectomy (PD). Methods We divided 116 consecutive patients who …

[HTML][HTML] Five days of postoperative antimicrobial therapy decreases infectious complications following pancreaticoduodenectomy in patients at risk for bile …

I Sourrouille, S Gaujoux, G Lacave, F Bert, S Dokmak… - HPB, 2013 - Elsevier
Objectives Pancreaticoduodenectomy (PD) is associated with high morbidity, in part as a
result of infectious complications increased by preoperative bile contamination. The aim of …