Metaproteomic and metabolomic approaches for characterizing the gut microbiome

DL Peters, W Wang, X Zhang, Z Ning, J Mayne… - …, 2019 - Wiley Online Library
The gut microbiome has been shown to play a significant role in human healthy and
diseased states. The dynamic signaling that occurs between the host and microbiome is …

The human gut microbiome and its dysfunctions through the meta‐omics prism

S Mondot, P Lepage - Annals of the New York Academy of …, 2016 - Wiley Online Library
The microorganisms inhabiting the human gut are abundant (1014 cells) and diverse
(approximately 500 species per individual). It is now acknowledged that the microbiota has …

The human microbiome and metabolomics: current concepts and applications

EBM Daliri, S Wei, DH Oh, BH Lee - Critical reviews in food science …, 2017 - Taylor & Francis
The mammalian gastrointestinal tract has co-developed with a large number of microbes in
a symbiotic relationship over millions of years. Recent studies indicate that indigenous …

Microbial metaproteomics for characterizing the range of metabolic functions and activities of human gut microbiota

W Xiong, PE Abraham, Z Li, C Pan, RL Hettich - Proteomics, 2015 - Wiley Online Library
The human gastrointestinal tract is a complex, dynamic ecosystem that consists of a carefully
tuned balance of human host and microbiota membership. The microbiome is not merely a …

Advancing functional and translational microbiome research using meta-omics approaches

X Zhang, L Li, J Butcher, A Stintzi, D Figeys - Microbiome, 2019 - Springer
The gut microbiome has emerged as an important factor affecting human health and
disease. The recent development of–omics approaches, including phylogenetic marker …

Metaproteomics study of the gut microbiome

LA Lai, Z Tong, R Chen, S Pan - Functional Proteomics: Methods and …, 2019 - Springer
Proteomics is a widely used method for defining the protein composition of a complex
sample. As this approach allows for identification and quantification of proteins across a …

Metabolome–microbiome crosstalk and human disease

KA Lee-Sarwar, J Lasky-Su, RS Kelly, AA Litonjua… - Metabolites, 2020 - mdpi.com
In this review, we discuss the growing literature demonstrating robust and pervasive
associations between the microbiome and metabolome. We focus on the gut microbiome …

Metaproteomics—An advantageous option in studies of host-microbiota interaction

O Karaduta, Z Dvanajscak, B Zybailov - Microorganisms, 2021 - mdpi.com
Gut microbiome contributes to host health by maintaining homeostasis, increasing digestive
efficiency, and facilitating the development of the immune system. Manipulating gut …

Metaproteomics: a strategy to study the taxonomy and functionality of the gut microbiota

Y Wang, Y Zhou, X Xiao, J Zheng, H Zhou - Journal of proteomics, 2020 - Elsevier
The gut microbiota is the largest and most complex microbial community in the human body.
Host-gut microbiota interactions have significant implications on health and disease. The …

[HTML][HTML] Gut microbiota profiling: metabolomics based approach to unravel compounds affecting human health

P Vernocchi, F Del Chierico, L Putignani - Frontiers in microbiology, 2016 - frontiersin.org
The gut microbiota is composed of a huge number of different bacteria, that produce a large
amount of compounds playing a key role in microbe selection and in the construction of a …