Prevalence and predictive value of intermittent viremia with combination HIV therapy

DV Havlir, R Bassett, D Levitan, P Gilbert, P Tebas… - Jama, 2001 - jamanetwork.com
ContextIn HIV-infected patients having virologic suppression (plasma HIV RNA< 50
copies/mL) with antiretroviral therapy, intermittent episodes of low-level viremia have been …

The natural history and clinical significance of intermittent viraemia in patients with initial viral suppression to< 400 copies/ml

PJ Easterbrook, N Ives, A Waters, J Mullen, S O'Shea… - Aids, 2002 - journals.lww.com
Objectives To determine the prevalence and prognostic significance of intermittent viraemia
(IV) in patients who attained an undetectable viral load (VL)< 400 copies/ml within 6 months …

Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy

DV Havlir, IC Marschner, MS Hirsch… - … England Journal of …, 1998 - Mass Medical Soc
Background Combination antiretroviral therapy with indinavir, zidovudine, and lamivudine
can suppress the level of human immunodeficiency virus (HIV) RNA in plasma below the …

Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART

RE Nettles, TL Kieffer, P Kwon, D Monie, Y Han… - Jama, 2005 - jamanetwork.com
ContextMany patients infected with human immunodeficiency virus type 1 (HIV-1) and
receiving highly active antiretroviral therapy experience intermittent episodes of detectable …

Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor–based or protease inhibitor–based highly active …

S Sungkanuparph, ET Overton… - Clinical infectious …, 2005 - academic.oup.com
Background. Intermittent episodes of detectable human immunodeficiency virus (HIV)
viremia (hereafter referred to as “blips”) are generally not predictive of subsequent virologic …

Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy

D Descamps, P Flandre, V Calvez, G Peytavin… - Jama, 2000 - jamanetwork.com
ContextIn the Trilège trial, following induction with a zidovudine, lamivudine, and indinavir
regimen, human immunodeficiency virus (HIV) replication was less suppressed by 2-drug …

Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive …

DV Havlir, MC Strain, M Clerici, C Ignacio… - Journal of …, 2003 - Am Soc Microbiol
To provide insight into the dynamics and source of residual viremia in human
immunodeficiency virus (HIV) patients successfully treated with antiretroviral therapy, 14 …

A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously untreated HIV …

G Pialoux, F Raffi, F Brun-Vezinet… - … England Journal of …, 1998 - Mass Medical Soc
Background The long-term effectiveness of potent three-drug antiretroviral regimens for the
treatment of human immunodeficiency virus type 1 (HIV-1) infection is limited by problems …

Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trial

SMART Study Group* - Annals of internal medicine, 2008 - acpjournals.org
Background: Episodic use of antiretroviral therapy guided by CD4+ cell counts is inferior to
continuous antiretroviral therapy. Objective: To determine whether reinitiating continuous …

Prevalence and clinical correlates of HIV viremia (blips') in patients with previous suppression below the limits of quantification

PA Sklar, DJ Ward, RK Baker, KC Wood, Z Gafoor… - Aids, 2002 - journals.lww.com
Objective: To examine the prevalence and clinical correlates of subsequently measurable
viremia in HIV-infected patients who have achieved viral suppression below the limits of …