Breast cancer surgery is known to cause severe acute postoperative pain, which can persist
for a long time. We administered nefopam preventively to patients undergoing lumpectomy …

Background We assessed whether intraoperative nefopam would reduce opioid
consumption and relieve postoperative pain in patients undergoing laparoscopic …

Nefopam, a centrally acting analgesic, has been used in the surgical setting in many
countries since the mid-1970s. However, clinical trials provide contflicting results for its …

Background Nefopam is a non-opioid, non-steroidal, centrally acting analgesic drug. The
concomitant use of opioids and nefopam is believed to have many advantages over the …

Background: The incidence of moderate to severe pain is high among patients undergoing
spinal surgery. Nefopam can be used as an adjuvant analgesic postoperatively after spine …

Background. Balanced postoperative analgesia combines non‐narcotic drugs and opioids.
We organized a large study to evaluate nefopam analgesia and tolerance in combination …

Background. Acute postoperative pain (APP) has a high incidence in breast surgery, and
opioids are the most commonly used drugs for its management; however, they are not free …

Background Nefopam is a centrally acting analgesic that is used to control pain. The aim of
this study was to find an appropriate dose of nefopam that demonstrates an analgesic effect …

A randomized, double-blind, placebo-controlled study was performed to assess the
analgesic efficacy of intramuscular nefopam hydrochloride after upper abdominal surgery …

Background: Pain control after laparoscopic cholecystectomy (LC) has become an important
topic. We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the …