Memory B cells

T Inoue, T Kurosaki - Nature Reviews Immunology, 2024 - nature.com
Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …

Memory B cells

T Kurosaki, K Kometani, W Ise - Nature Reviews Immunology, 2015 - nature.com
The immune system can remember a previously experienced pathogen and can evoke an
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …

Human B cell memory

A Lanzavecchia, F Sallusto - Current opinion in immunology, 2009 - Elsevier
Following an immune response two types of differentiated B cells persist in the memory pool:
plasma cells, which confer immediate protection by the secretion of specific antibodies; and …

Generation of memory B cells and their reactivation

T Inoue, I Moran, R Shinnakasu, TG Phan… - Immunological …, 2018 - Wiley Online Library
The successful establishment of humoral memory response depends on at least two layers
of defense. Pre‐existing protective antibodies secreted by long‐lived plasma cells act as a …

Phenotypic and functional heterogeneity of human memory B cells

I Sanz, C Wei, FEH Lee, J Anolik - Seminars in immunology, 2008 - Elsevier
Memory B cells are more heterogeneous than previously thought. Given that B cells play
powerful antibody-independent effector functions, it seems reasonable to assume division of …

Heterogeneity in the differentiation and function of memory B cells

JJ Taylor, MK Jenkins, KA Pape - Trends in immunology, 2012 - cell.com
Vaccines that induce neutralizing antibodies have led to the eradication of small pox and
have severely reduced the prevalence of many other infections. However, even the most …

[HTML][HTML] Generation of high quality memory B cells

T Inoue, R Shinnakasu, T Kurosaki - Frontiers in immunology, 2022 - frontiersin.org
Protection against pathogen re-infection is mediated, in large part, by two humoral cellular
compartments, namely, long-lived plasma cells and memory B cells. Recent data have …

[HTML][HTML] Remembrance of things past: long-term B cell memory after infection and vaccination

AKE Palm, C Henry - Frontiers in immunology, 2019 - frontiersin.org
The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …

Memory B cells of mice and humans

F Weisel, M Shlomchik - Annual review of immunology, 2017 - annualreviews.org
We comprehensively review memory B cells (MBCs), covering the definition of MBCs and
their identities and subsets, how MBCs are generated, where they are localized, how they …

[HTML][HTML] B cell memory: building two walls of protection against pathogens

M Akkaya, K Kwak, SK Pierce - Nature Reviews Immunology, 2020 - nature.com
Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such
protection is mediated, in large part, by two main B cell memory 'walls'—namely, long-lived …