A distributed and efficient population code of mixed selectivity neurons for flexible navigation decisions

S Kira, H Safaai, AS Morcos, S Panzeri… - Nature …, 2023 - nature.com
Decision-making requires flexibility to rapidly switch one's actions in response to sensory
stimuli depending on information stored in memory. We identified cortical areas and neural …

[HTML][HTML] Shared and specialized coding across posterior cortical areas for dynamic navigation decisions

SY Tseng, SN Chettih, C Arlt, R Barroso-Luque… - Neuron, 2022 - cell.com
Animals adaptively integrate sensation, planning, and action to navigate toward goal
locations in ever-changing environments, but the functional organization of cortex …

Cognitive experience alters cortical involvement in goal-directed navigation

C Arlt, R Barroso-Luque, S Kira, CA Bruno, N Xia… - Elife, 2022 - elifesciences.org
Neural activity in the mammalian cortex has been studied extensively during decision tasks,
and recent work aims to identify under what conditions cortex is actually necessary for these …

Distributed context-dependent choice information in mouse posterior cortex

JG Orlandi, M Abdolrahmani, R Aoki… - Nature …, 2023 - nature.com
Choice information appears in multi-area brain networks mixed with sensory, motor, and
cognitive variables. In the posterior cortex—traditionally implicated in decision computations …

Neuronal adaptation reveals a suboptimal decoding of orientation tuned populations in the mouse visual cortex

M Jin, JM Beck, LL Glickfeld - Journal of Neuroscience, 2019 - Soc Neuroscience
Sensory information is encoded by populations of cortical neurons. Yet, it is unknown how
this information is used for even simple perceptual choices such as discriminating …

Rapid synaptic plasticity contributes to a learned conjunctive code of position and choice-related information in the hippocampus

X Zhao, CL Hsu, N Spruston - Neuron, 2022 - cell.com
To successfully perform goal-directed navigation, animals must know where they are and
what they are doing—eg, looking for water, bringing food back to the nest, or escaping from …

A reservoir of foraging decision variables in the mouse brain

F Cazettes, L Mazzucato, M Murakami, JP Morais… - Nature …, 2023 - nature.com
In any given situation, the environment can be parsed in different ways to yield decision
variables (DVs) defining strategies useful for different tasks. It is generally presumed that the …

The impact of visual cues, reward, and motor feedback on the representation of behaviorally relevant spatial locations in primary visual cortex

JMP Pakan, SP Currie, L Fischer, NL Rochefort - Cell reports, 2018 - cell.com
The integration of visual stimuli and motor feedback is critical for successful visually guided
navigation. These signals have been shown to shape neuronal activity in the primary visual …

Behavior-dependent directional tuning in the human visual-navigation network

M Nau, T Navarro Schröder, M Frey… - Nature communications, 2020 - nature.com
The brain derives cognitive maps from sensory experience that guide memory formation and
behavior. Despite extensive efforts, it still remains unclear how the underlying population …

Behaviorally relevant decision coding in primary somatosensory cortex neurons

C Buetfering, Z Zhang, M Pitsiani, J Smallridge… - Nature …, 2022 - nature.com
Primary sensory cortex is thought to process incoming sensory information, while decision
variables important for driving behavior are assumed to arise downstream in the processing …