Molecular epidemiology of Plasmodium falciparum kelch13 mutations in Senegal determined by using targeted amplicon deep sequencing
E Talundzic, YD Ndiaye, AB Deme… - Antimicrobial agents …, 2017 - Am Soc Microbiol
The emergence of Plasmodium falciparum resistance to artemisinin in Southeast Asia
threatens malaria control and elimination activities worldwide. Multiple polymorphisms in the …
threatens malaria control and elimination activities worldwide. Multiple polymorphisms in the …
[HTML][HTML] Distribution of Plasmodium falciparum K13 gene polymorphisms across transmission settings in Ghana
Malaria is a significant global health concern, with a majority of cases in Sub-Saharan
African nations. Numerous antimalarial drugs have been developed to counter the rampant …
African nations. Numerous antimalarial drugs have been developed to counter the rampant …
[HTML][HTML] Increase in Kelch 13 polymorphisms in Plasmodium falciparum, southern Rwanda
C Bergmann, W van Loon, F Habarugira… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous
mutations in the Kelch 13 (K13) propeller domain. We found that 12.1%(8/66) of clinical P …
mutations in the Kelch 13 (K13) propeller domain. We found that 12.1%(8/66) of clinical P …
[HTML][HTML] Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal
A Gaye, M Sy, T Ndiaye, KJ Siddle, DJ Park, AB Deme… - Malaria Journal, 2020 - Springer
Abstract Background In 2006, the Senegalese National Malaria Control Programme
recommended artemisinin-based combination therapy (ACT) with artemether–lumefantrine …
recommended artemisinin-based combination therapy (ACT) with artemether–lumefantrine …
[HTML][HTML] K-13 propeller gene polymorphisms isolated between 2014 and 2017 from Cameroonian Plasmodium falciparum malaria patients
CE Eboumbou Moukoko, F Huang, SE Nsango… - PLoS …, 2019 - journals.plos.org
The emergence of artemisinin-resistant parasites since the late 2000s at the border of
Cambodia and Thailand poses serious threats to malaria control globally, particularly in …
Cambodia and Thailand poses serious threats to malaria control globally, particularly in …
Spatial and molecular mapping of Pfkelch13 gene polymorphism in Africa in the era of emerging Plasmodium falciparum resistance to artemisinin: a systematic review
NK Kayiba, DM Yobi… - The Lancet Infectious …, 2021 - thelancet.com
The spread of Plasmodium falciparum isolates carrying mutations in the kelch13 (Pfkelch13)
gene associated with artemisinin resistance (PfART-R) in southeast Asia threatens malaria …
gene associated with artemisinin resistance (PfART-R) in southeast Asia threatens malaria …
[HTML][HTML] Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012–2013
M Torrentino-Madamet, B Fall, N Benoit, C Camara… - Malaria journal, 2014 - Springer
Abstract Background The emergence of Plasmodium falciparum resistance to artemisinin
and its derivatives, manifested as delayed parasite clearance following the treatment, has …
and its derivatives, manifested as delayed parasite clearance following the treatment, has …
[HTML][HTML] Molecular surveillance of Kelch 13 polymorphisms in Plasmodium falciparum isolates from Kenya and Ethiopia
Background Timely molecular surveillance of Plasmodium falciparum kelch 13 (k13) gene
mutations is essential for monitoring the emergence and stemming the spread of artemisinin …
mutations is essential for monitoring the emergence and stemming the spread of artemisinin …
[HTML][HTML] Molecular profiling of the artemisinin resistance Kelch 13 gene in Plasmodium falciparum from Nigeria
Accurate assessment and monitoring of the Plasmodium falciparum Kelch 13 (pfk13) gene
associated with artemisinin resistance is critical to understand the emergence and spread of …
associated with artemisinin resistance is critical to understand the emergence and spread of …
[HTML][HTML] Polymorphisms in the K13-propeller gene in artemisinin-susceptible Plasmodium falciparum parasites from Bougoula-Hameau and Bandiagara, Mali
Artemisinin-resistant Plasmodium falciparum malaria has been documented in southeast
Asia and may already be spreading in that region. Molecular markers are important tools for …
Asia and may already be spreading in that region. Molecular markers are important tools for …