Sex-Specific Pathways From Prenatal Maternal Inflammation to Adolescent Depressive Symptoms

E Lipner, N Mac Giollabhui, EC Breen, BA Cohn… - JAMA …, 2024 - jamanetwork.com
Importance Prenatal maternal inflammation has been associated with major depressive
disorder in offspring in adulthood as well as with internalizing and externalizing symptoms in …

Maternal inflammation during pregnancy and offspring psychiatric symptoms in childhood: Timing and sex matter

N Mac Giollabhui, EC Breen, SK Murphy… - Journal of psychiatric …, 2019 - Elsevier
Objective Maternal infection during pregnancy has been associated with increased risk of
offspring psychopathology, including depression. As most infections do not cross the …

Maternal prenatal depression predicts infant negative affect via maternal inflammatory cytokine levels

HC Gustafsson, EL Sullivan, EK Nousen… - Brain, behavior, and …, 2018 - Elsevier
Maternal depressive symptoms during pregnancy are associated with risk for offspring
emotional and behavioral problems, but the mechanisms by which this association occurs …

[HTML][HTML] Prenatal maternal depression is associated with offspring inflammation at 25 years: a prospective longitudinal cohort study

DT Plant, S Pawlby, D Sharp, PA Zunszain… - Translational …, 2016 - nature.com
Animal studies and a handful of prospective human studies have demonstrated that young
offspring exposed to maternal prenatal stress show abnormalities in immune parameters …

Prenatal maternal Inflammation, childhood cognition and adolescent depressive symptoms

MR Pike, E Lipner, KJ O'Brien, EC Breen… - Brain, Behavior, and …, 2024 - Elsevier
Background Accumulating evidence indicates that higher prenatal maternal inflammation is
associated with increased depression risk in adolescent and adult-aged offspring. Prenatal …

Expression of inflammatory markers in women with perinatal depressive symptoms

R Buglione-Corbett, KM Deligiannidis, K Leung… - Archives of women's …, 2018 - Springer
Abstract Perinatal depression affects 10–20% of women and is associated with poor
outcomes for mother and child. Inflammation is associated with depression in non-pregnant …

[HTML][HTML] Prenatal immune programming of the sex-dependent risk for major depression

SE Gilman, S Cherkerzian, SL Buka, J Hahn… - Translational …, 2016 - nature.com
Maternal immune functioning during pregnancy contributes to sex-dependent deficits in
neurodevelopment and to behaviors associated with affective traits in preclinical studies …

Prenatal and childhood adverse life events, inflammation and depressive symptoms across adolescence

E Flouri, M Francesconi, E Midouhas… - Journal of affective …, 2020 - Elsevier
Background No study has investigated the role of inflammation in explaining the association
between early exposures to adverse life events and depressive symptoms in adolescence …

Maternal depressive symptoms during and after pregnancy and psychiatric problems in children

M Lahti, K Savolainen, S Tuovinen, AK Pesonen… - Journal of the American …, 2017 - Elsevier
Objective Maternal depressive symptoms during pregnancy are associated with increased
risk of psychiatric problems in children. A more precise understanding of the timing of the …

Associations between prenatal maternal stress, maternal inflammation during pregnancy, and children's internalizing and externalizing symptoms throughout …

ZM Clayborne, R Zou, SE Gilman… - Brain, Behavior, and …, 2023 - Elsevier
Background Maternal immune activation is a potential mechanism underlying associations
between maternal stress during pregnancy and offspring mental health problems. This study …