Secreted phospholipase A2 revisited

M Murakami, Y Taketomi, H Sato… - The journal of …, 2011 - academic.oup.com
Abstract Phospholipase A2 (PLA2) catalyses the hydrolysis of the sn-2 position of
glycerophospholipids to yield fatty acids and lysophospholipids. So far, more than 30 …

Emerging roles of secreted phospholipase A2 enzymes: an update

M Murakami, G Lambeau - Biochimie, 2013 - Elsevier
Phospholipase A2 (PLA2) enzymes catalyze the hydrolysis of the sn-2 position of
glycerophospholipids to produce free fatty acids and lysophospholipids. More than one third …

A new era of secreted phospholipase A2

M Murakami, H Sato, Y Miki, K Yamamoto… - Journal of lipid …, 2015 - ASBMB
Among more than 30 members of the phospholipase A 2 (PLA 2) superfamily, secreted PLA
2 (sPLA 2) enzymes represent the largest family, being Ca 2+-dependent low-molecular …

Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice

M Murakami, Y Taketomi, C Girard, K Yamamoto… - Biochimie, 2010 - Elsevier
Among the emerging phospholipase A2 (PLA2) superfamily, the secreted PLA2 (sPLA2)
family consists of low-molecular-mass, Ca2+-requiring extracellular enzymes with a His-Asp …

Emerging roles of secreted phospholipase A2 enzymes: the 3rd edition

M Murakami, Y Taketomi, Y Miki, H Sato, K Yamamoto… - Biochimie, 2014 - Elsevier
Within the phospholipase A 2 (PLA 2) superfamily, secreted PLA 2 (sPLA 2) enzymes
comprise the largest family that contains 11 to 12 mammalian isoforms with a conserved His …

Phospholipase A2

M Murakami, I Kudo - The journal of biochemistry, 2002 - academic.oup.com
Phospholipase A2 (PLA2 catalyzes the hydrolysis of the sn-2 position of membrans
glyerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including …

Novel functions of phospholipase A2s: Overview

M Murakami - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2019 - Elsevier
Abstract The phospholipase A 2 (PLA 2) family comprises a group of lipolytic enzymes that
typically hydrolyze the sn-2 position of (glycerol) phospholipids to give rise to fatty acids and …

Phospholipase A2 enzymes

I Kudo, M Murakami - Prostaglandins & other lipid mediators, 2002 - Elsevier
Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane
glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including …

Updating Phospholipase A2 Biology

M Murakami, H Sato, Y Taketomi - Biomolecules, 2020 - mdpi.com
The phospholipase A2 (PLA2) superfamily contains more than 50 enzymes in mammals that
are subdivided into several distinct families on a structural and biochemical basis. In …

Biochemistry and Physiology of Mammalian Secreted Phospholipases A2

G Lambeau, MH Gelb - Annu. Rev. Biochem., 2008 - annualreviews.org
Phospholipases A2 (PLA2s) are esterases that hydrolyze the sn-2 ester of
glycerophospholipids and constitute one of the largest families of lipid hydrolyzing enzymes …