Cerebral oedema is a devastating consequence of acute liver failure (ALF) and may be
associated with the development of intracranial hypertension and death. In ALF, some …

Brain edema and associated increase in intracranial pressure continue to be lethal
complications of acute liver failure (ALF). Abundant evidence suggests that the edema in …

Continued elucidation of the mechanisms of brain edema in acute liver failure (ALF) has
established ammonia and the astrocyte as major players in its pathogenesis. The …

Cerebral edema is a potential life-threatening complication in patients with acute liver failure
who progress to grade III/IV encephalopathy. The incidence is variably reported but appears …

Brain edema and the associated increase in intracranial pressure are potentially lethal
complications of acute liver failure (ALF). Astrocyte swelling (cytotoxic edema) represents a …

Hepatic encephalopathy and brain edema are important complications in the course of a
patient with acute liver failure. Presumed unrelated for many years, increasing evidence …

Hepatic encephalopathy (HE) in acute liver injury signifies a serious prognosis. Brain edema
and intracranial hypertension are major causes of death in this syndrome. Comparison of …

It is generally accepted that astrocyte swelling forms the major anatomic substrate of the
edema associated with acute liver failure (ALF) and that ammonia represents a major …

Neuropathologic investigations in acute liver failure (ALF) reveal significant alterations to
neuroglia consisting of swelling of astrocytes leading to cytotoxic brain edema and …

Acute liver failure (ALF) is a condition with an unfavourable prognosis. Multiorgan failure
and circulatory collapse are frequent causes of death, but cerebral edema and intracranial …