[HTML][HTML] Periostin promotes colorectal tumorigenesis through integrin-FAK-Src pathway-mediated YAP/TAZ activation

H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu… - Cell reports, 2020 - cell.com
Periostin is a multifunctional extracellular matrix protein involved in various inflammatory
diseases and tumor metastasis; however, evidence regarding whether and how periostin …

[HTML][HTML] Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway

S Bao, G Ouyang, X Bai, Z Huang, C Ma, M Liu, R Shao… - Cancer cell, 2004 - cell.com
Molecular mechanisms associated with tumor metastasis remain poorly understood. Here
we report that acquired expression of periostin by colon cancer cells greatly promoted …

[HTML][HTML] Periostin, a multifunctional matricellular protein in inflammatory and tumor microenvironments

AY Liu, H Zheng, G Ouyang - Matrix biology, 2014 - Elsevier
The behavior and fate of cells in tissues largely rely upon their cross-talk with the tissue
microenvironment including neighboring cells, the extracellular matrix (ECM), and soluble …

Periostin: an emerging activator of multiple signaling pathways

Z Wang, J An, D Zhu, H Chen, A Lin, J Kang… - Journal of cell …, 2022 - Springer
Matricellular proteins are responsible for regulating the microenvironment, the behaviors of
surrounding cells, and the homeostasis of tissues. Periostin (POSTN), a non-structural …

[HTML][HTML] Matricellular protein periostin contributes to hepatic inflammation and fibrosis

Y Huang, W Liu, H Xiao, A Maitikabili, Q Lin… - The American journal of …, 2015 - Elsevier
Periostin actively contributes to tissue injury, fibrosis, atherosclerosis, and inflammatory
diseases; however, its role in hepatic fibrosis is unclear. Herein, we revealed that periostin …

[HTML][HTML] Periostin: biology and function in cancer

S Dorafshan, M Razmi, S Safaei, E Gentilin… - Cancer Cell …, 2022 - Springer
Periostin (POSTN), a member of the matricellular protein family, is a secreted adhesion-
related protein produced in the periosteum and periodontal ligaments. Matricellular proteins …

The multifaceted role of periostin in tumorigenesis

K Ruan, S Bao, G Ouyang - Cellular and molecular life sciences, 2009 - Springer
Periostin, also called osteoblast-specific factor 2 (OSF-2), is a member of the fasciclin family
and a disulfide-linked cell adhesion protein that has been shown to be expressed …

Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway

G Ouyang, M Liu, K Ruan, G Song, Y Mao, S Bao - Cancer letters, 2009 - Elsevier
Periostin is a secreted protein and has been shown to be frequently overexpressed in
various types of human cancers. We have previously reported that periostin potently …

Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies

IT Tai, M Dai, LB Chen - Carcinogenesis, 2005 - academic.oup.com
Several factors have been shown to promote the growth of colorectal cancers. Here, we
provide evidence that periostin, a protein with structural and sequence homology with a TGF …

[HTML][HTML] The niche component periostin is produced by cancer-associated fibroblasts, supporting growth of gastric cancer through ERK activation

Y Kikuchi, A Kunita, C Iwata, D Komura… - The American journal of …, 2014 - Elsevier
Overexpression of periostin (POSTN), an extracellular matrix protein, has been observed in
several cancers. We investigated the importance of POSTN in gastric cancer. Genome-wide …