Objective: Alcohol use disorder (AUD) and chronic pain are widespread conditions with
extensive public health burden. This review seeks to describe neuroanatomical links and …

Alcohol is an effective and widely utilized analgesic. However, the chronic use of alcohol
can actually facilitate nociceptive sensitivity over time, a condition known as hyperalgesia …

An association between chronic pain conditions and alcohol dependence has been
revealed in numerous studies with episodes of alcohol abuse antedating chronic pain in …

Alcohol use disorder (AUD) and chronic pain are enduring and devastating conditions that
share an intersecting epidemiology and neurobiology. Chronic alcohol use itself can …

Dysregulation of pain neurocircuitry and neurochemistry has been increasingly recognized
as playing a critical role in a diverse spectrum of diseases including migraine, fibromyalgia …

Addiction, or substance use disorder (SUD), is a devastating psychiatric disease composed
of multiple elemental features. As a biobehavioral disorder, escalation of drug and/or alcohol …

Alcohol use disorder (AUD) is highly comorbid with chronic pain (CP). Evidence has
suggested that neuroadaptive processes characterized by reward deficit and stress surfeit …

Aims A close and bidirectional relationship between alcohol consumption and pain has
been previously reported and discussed in influential reviews. The goal of the present …

Opioids and alcohol are widely used to relieve pain, with their analgesic efficacy stemming
from rapid actions on both spinal and supraspinal nociceptive centers. As an extension of …

Despite accumulating evidence indicating reciprocal interrelations between pain and
alcohol consumption, no prior work has examined pain as a proximal antecedent of drinking …