Control of microtubule organization and dynamics: two ends in the limelight
A Akhmanova, MO Steinmetz - Nature reviews Molecular cell biology, 2015 - nature.com
Microtubules have fundamental roles in many essential biological processes, including cell
division and intracellular transport. They assemble and disassemble from their two ends …
division and intracellular transport. They assemble and disassemble from their two ends …
Microtubule minus-end-targeting proteins
A Akhmanova, CC Hoogenraad - Current Biology, 2015 - cell.com
Microtubules are cytoskeletal filaments that are intrinsically polarized, with two structurally
and functionally distinct ends, the plus end and the minus end. Over the last decade …
and functionally distinct ends, the plus end and the minus end. Over the last decade …
Microtubule minus-end regulation at a glance
A Akhmanova, MO Steinmetz - Journal of cell science, 2019 - journals.biologists.com
Microtubules are cytoskeletal filaments essential for numerous aspects of cell physiology.
They are polarized polymeric tubes with a fast growing plus end and a slow growing minus …
They are polarized polymeric tubes with a fast growing plus end and a slow growing minus …
An EB1-binding motif acts as a microtubule tip localization signal
S Honnappa, SM Gouveia, A Weisbrich, FF Damberger… - Cell, 2009 - cell.com
Microtubules are filamentous polymers essential for cell viability. Microtubule plus-end
tracking proteins (+ TIPs) associate with growing microtubule plus ends and control …
tracking proteins (+ TIPs) associate with growing microtubule plus ends and control …
CLIPs and CLASPs and cellular dynamics
N Galjart - Nature reviews Molecular cell biology, 2005 - nature.com
The dynamic properties of microtubules are regulated by plus-end tracking proteins (+ TIPs),
which associate with the distal ends of microtubules. Among the+ TIPs are cytoplasmic linker …
which associate with the distal ends of microtubules. Among the+ TIPs are cytoplasmic linker …
Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin
MC Hendershott, RD Vale - Proceedings of the National …, 2014 - National Acad Sciences
The microtubule (MT) cytoskeleton plays an essential role in mitosis, intracellular transport,
cell shape, and cell migration. The assembly and disassembly of MTs, which can occur …
cell shape, and cell migration. The assembly and disassembly of MTs, which can occur …
CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites
The microtubule cytoskeleton is crucial for the internal organization of eukaryotic cells.
Several microtubule-associated proteins link microtubules to subcellular structures. A …
Several microtubule-associated proteins link microtubules to subcellular structures. A …
Microtubule tip-interacting proteins: a view from both ends
K Jiang, A Akhmanova - Current opinion in cell biology, 2011 - Elsevier
Microtubule ends serve as sites of tubulin addition and removal, and at the same time play
crucial roles in microtubule capture, stabilization and attachment to different cellular …
crucial roles in microtubule capture, stabilization and attachment to different cellular …
Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1
KC Slep, RD Vale - Molecular cell, 2007 - cell.com
Microtubule plus end binding proteins (+ TIPs) localize to the dynamic plus ends of
microtubules, where they stimulate microtubule growth and recruit signaling molecules …
microtubules, where they stimulate microtubule growth and recruit signaling molecules …
Tracking the ends: a dynamic protein network controls the fate of microtubule tips
A Akhmanova, MO Steinmetz - Nature reviews Molecular cell biology, 2008 - nature.com
Microtubule plus-end tracking proteins (+ TIPs) are a diverse group of evolutionarily
conserved cellular factors that accumulate at the ends of growing microtubules. They form …
conserved cellular factors that accumulate at the ends of growing microtubules. They form …