Copper (ii)-infused porphyrin MOF: maximum scavenging GSH for enhanced photodynamic disruption of bacterial biofilm

Y Zhang, L Li, H Liu, H Zhang, M Wei… - Journal of Materials …, 2024 - pubs.rsc.org
Bacterial biofilm infection is a serious obstacle to clinical therapeutics. Photodynamic
therapy (PDT) plays a dynamic role in combating biofilm infection by utilizing reactive …

Porphyrin MOF dots–based, function‐adaptive nanoplatform for enhanced penetration and photodynamic eradication of bacterial biofilms

Q Deng, P Sun, L Zhang, Z Liu, H Wang… - Advanced Functional …, 2019 - Wiley Online Library
Recently, antimicrobial photodynamic therapy (aPDT) has been considered as an attractive
treatment option for biofilms ablation. However, even very efficient photosensitizers (PSs) …

Multi‐Mechanism Antibacterial Strategies Enabled by Synergistic Activity of Metal–Organic Framework‐Based Nanosystem for Infected Tissue Regeneration

W Xie, J Chen, X Cheng, H Feng, X Zhang, Z Zhu… - Small, 2023 - Wiley Online Library
Drug‐resistant bacterial infection impairs tissue regeneration and is a challenging clinical
problem. Metal–organic frameworks (MOFs)‐based photodynamic therapy (PDT) opens up …

Titanium incorporation into Zr‐porphyrinic metal–organic frameworks with enhanced antibacterial activity against multidrug‐resistant pathogens

M Chen, Z Long, R Dong, L Wang, J Zhang, S Li… - Small, 2020 - Wiley Online Library
This study uses metal–organic frameworks (MOFs) alone without any added antibacterial
ingredients as the nonantibiotic agent for photodynamic therapy (PDT) of chronic wounds …

An injectable multifunctional hydrogel for eradication of bacterial biofilms and wound healing

T Du, Z Xiao, G Zhang, L Wei, J Cao, Z Zhang, X Li… - Acta biomaterialia, 2023 - Elsevier
Wound treatment is largely influenced by pre-existing hypoxic microenvironments and
biofilms, which can severely diminish the efficacy of phototherapy, suggesting the …

Photodynamic inactivation of bacteria and biofilms with benzoselenadiazole-doped metal-organic frameworks

L Luan, L Du, W Shi, Y Li, Q Zhang - Molecules, 2022 - mdpi.com
Bacterial biofilms are difficult to treat due to their resistance to traditional antibiotics.
Although photodynamic therapy (PDT) has made significant progress in biomedical …

Integrating porphyrinic metal-organic frameworks in nanofibrous carrier for photodynamic antimicrobial application

H Zhang, Z Xu, Y Mao, Y Zhang, Y Li, J Lao, L Wang - Polymers, 2021 - mdpi.com
The rise and spread of antimicrobial resistance is creating an ever greater challenge in
wound management. Nanofibrous membranes (NFMs) incorporated with antibiotics have …

Size engineering of 2D MOF nanosheets for enhanced photodynamic antimicrobial therapy

B Xue, X Geng, H Cui, H Chen, Z Wu, H Chen… - Chinese Chemical …, 2023 - Elsevier
Although porphyrin-based metal-organic frameworks (MOFs) have been widely explored as
photosensitizers for photodynamic therapy, how the size will affect the light-induced catalytic …

Biofilm Microenvironment-Mediated MoS2 Nanoplatform with Its Photothermal/Photodynamic Synergistic Antibacterial Molecular Mechanism and Wound Healing …

W Jin, P Song, Y Wu, Y Tao, K Yang, L Gui… - ACS Biomaterials …, 2022 - ACS Publications
Drug-resistant bacterial infections pose a serious threat to human public health. Biofilm
formation is one of the main factors contributing to the development of bacterial resistance …

Synergistic Photodynamic/Antibiotic Therapy with Photosensitive MOF-Based Nanoparticles to Eradicate Bacterial Biofilms

L Du, W Shi, X Hao, L Luan, S Wang, J Lu, Q Zhang - Pharmaceutics, 2023 - mdpi.com
Bacterial biofilms pose a serious threat to human health, as they prevent the penetration of
antimicrobial agents. Developing nanocarriers that can simultaneously permeate biofilms …