[HTML][HTML] First multimodal, three-dimensional, image-guided total marrow irradiation model for preclinical bone marrow transplantation studies
D Zuro, SS Madabushi, J Brooks, BT Chen… - International Journal of …, 2021 - Elsevier
Purpose Total marrow irradiation (TMI) has significantly advanced radiation conditioning for
hematopoietic cell transplantation in hematological malignancies by reducing conditioning …
hematopoietic cell transplantation in hematological malignancies by reducing conditioning …
Total marrow irradiation reduces organ damage and enhances tissue repair with the potential to increase the targeted dose of bone marrow in both young and old …
JE Lim, S Sargur Madabushi, P Vishwasrao… - Frontiers in …, 2022 - frontiersin.org
Total body irradiation (TBI) is a commonly used conditioning regimen for hematopoietic stem
cell transplant (HCT), but dose heterogeneity and long-term organ toxicity pose significant …
cell transplant (HCT), but dose heterogeneity and long-term organ toxicity pose significant …
Feasibility of a Novel Sparse Orthogonal Collimator–Based Preclinical Total Marrow Irradiation for Enhanced Dosimetric Conformality
AMH Abdelhamid, L Jiang, D Zuro, A Liu… - Frontiers in …, 2022 - frontiersin.org
Total marrow irradiation (TMI) has significantly improved radiation conditioning for
hematopoietic cell transplantation in hematologic diseases by reducing conditioning …
hematopoietic cell transplantation in hematologic diseases by reducing conditioning …
Total marrow irradiation: redefining the role of radiotherapy in bone marrow transplantation
JYC Wong - Total Marrow Irradiation: A Comprehensive Review, 2020 - Springer
Total body irradiation (TBI) is an important part of the conditioning regimen for patients
undergoing hematopoietic cell transplantation (HCT), but its use is declining due to a lack of …
undergoing hematopoietic cell transplantation (HCT), but its use is declining due to a lack of …
Total marrow irradiation in hematopoietic stem cell transplantation for hematologic malignancies
MN Kerbauy, LJ Arcuri, SL Favareto… - Frontiers in …, 2023 - frontiersin.org
Total body irradiation (TBI) has been an essential component of the conditioning regimen in
hematopoietic cell transplantation for many years. However, higher doses of TBI reduce …
hematopoietic cell transplantation for many years. However, higher doses of TBI reduce …
[HTML][HTML] Targeted total marrow irradiation using three-dimensional image-guided tomographic intensity-modulated radiation therapy: an alternative to standard total …
JYC Wong, A Liu, T Schultheiss, L Popplewell… - Biology of Blood and …, 2006 - Elsevier
Total body irradiation (TBI) is an important part of bone marrow transplantation conditioning
regimens. In TBI, dose escalation is difficult, because of associated normal organ toxicities …
regimens. In TBI, dose escalation is difficult, because of associated normal organ toxicities …
[HTML][HTML] Early assessment of dosimetric and biological differences of total marrow irradiation versus total body irradiation in rodents
S Hui, Y Takahashi, SG Holtan, R Azimi… - Radiotherapy and …, 2017 - Elsevier
Purpose To develop a murine total marrow irradiation (TMI) model in comparison with the
total body irradiation (TBI) model. Materials and methods Myeloablative TMI and TBI were …
total body irradiation (TBI) model. Materials and methods Myeloablative TMI and TBI were …
[HTML][HTML] Effects of sublethal irradiation on patterns of engraftment after murine bone marrow transplantation
J Andrade, S Ge, G Symbatyan, MS Rosol… - Biology of Blood and …, 2011 - Elsevier
Attempts to reduce the toxicity of hematopoietic stem cell transplantation have led to the use
of various immunosuppressive, yet nonmyeloablative preparative regimens that often …
of various immunosuppressive, yet nonmyeloablative preparative regimens that often …
Utilizing organ-sparing marrow-targeted irradiation (OSMI) to condition patients with high-risk hematologic malignancies prior to allogeneic hematopoietic stem cell …
MX Welliver, S Vasu, M Weldon, W Zoller… - International Journal of …, 2018 - redjournal.org
Results Since July 2015 a total of 21 pts have been accrued (4 in cohort 1; 7 in cohort 2; 10
in cohort 3) and 16 total pts were treated. There are 10 AML, 4 ALL and 2 MDS pts. With a …
in cohort 3) and 16 total pts were treated. There are 10 AML, 4 ALL and 2 MDS pts. With a …
Maintain Efficacy and Spare Toxicity: Traditional and New Radiation-Based Conditioning Regimens in Hematopoietic Stem Cell Transplantation
I Dogliotti, M Levis, A Martin, S Bartoncini, F Felicetti… - Cancers, 2024 - mdpi.com
Simple Summary We discussed the potential long-term toxicities associated with total body
irradiation, its current indications, and the technical advances in radiotherapy that have …
irradiation, its current indications, and the technical advances in radiotherapy that have …