High levels of reactive oxygen species such as hydrogen peroxide (H 2 O 2) cause oxidative
stress in the lens and lead to cataractogenesis. The present investigation was undertaken to …

The scope of this investigation was to understand the role of aquaporin 5 (AQP5) for
maintaining lens transparency and homeostasis. Studies were conducted using lenses of …

Aquaporins (AQPs), by playing essential roles in the maintenance of ocular lens
homeostasis, contribute to the establishment and maintenance of the overall optical …

Cataract and presbyopia are the leading cause of vision loss and impaired vision,
respectively, worldwide. Changes in lens biochemistry and physiology with age are …

Until recently, the lens was thought to express only two aquaporin (AQP) water channels,
AQP1 and AQP0. In this study we confirm lenticular AQP5 protein expression by Western …

Aquaporins (AQPs) constitute a major conduit for movement of water across plasma
membranes. AQP0 is expressed in the fiber cells and is critical for lens transparency and …

purpose. To investigate the involvement of aquaporin (AQP)-1 in lens epithelial cell water
permeability and maintenance of lens transparency in experimental models of cataract …

In this work we have analyzed the expression levels of the main aquaporins (AQPs)
expressed in human lens epithelial cells (HLECs) using 112 samples from patients treated …

The aquaporin (AQP) transmembrane proteins facilitate the movement of water across the
plasma membrane. In the lens, AQP0 is expressed in fiber cells and AQP1 in the epithelium …

Abstract Aquaporin 0 (AQP0) is a transmembrane channel that constitutes∼ 45% of the total
membrane protein of the fiber cells in mammalian lens. It is critical for lens transparency and …