[HTML][HTML] Development of a prognostic index based on an immunogenomic landscape analysis of papillary thyroid cancer

P Lin, Y Guo, L Shi, X Li, H Yang, Y He, Q Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer,
and inflammation relates significantly to its initiation and prognosis. Systematic exploration …

Characterization of immune landscape in papillary thyroid cancer reveals distinct tumor immunogenicity and implications for immunotherapy

J Sun, R Shi, X Zhang, D Fang, J Rauch, S Lu… - …, 2021 - Taylor & Francis
Although the vast majority of patients with papillary thyroid cancer (PTC) have a favorable
prognosis when conventional treatments are implemented, local recurrence and distant …

[HTML][HTML] Immune landscape of papillary thyroid cancer and immunotherapeutic implications

KJ Na, H Choi - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Although papillary thyroid cancer (PTC) is curable with excellent survival rate, patients with
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …

[HTML][HTML] Immune cell confrontation in the papillary thyroid carcinoma microenvironment

Z Xie, X Li, Y He, S Wu, S Wang, J Sun, Y He… - Frontiers in …, 2020 - frontiersin.org
Background Papillary thyroid cancer has been associated with chronic inflammation. A
systematic understanding of immune cell infiltration in PTC is essential for subsequent …

[HTML][HTML] Immune gene signature delineates a subclass of papillary thyroid cancer with unfavorable clinical outcomes

K Kim, S Jeon, TM Kim, CK Jung - Cancers, 2018 - mdpi.com
Papillary thyroid carcinoma (PTC) represents a heterogeneous disease with diverse clinical
outcomes highlighting a need to identify robust biomarkers with clinical relevance. We …

Immune profiling of thyroid carcinomas suggests the existence of two major phenotypes: an ATC-like and a PDTC-like

R Giannini, S Moretti, C Ugolini… - The Journal of …, 2019 - academic.oup.com
Objectives The understanding of the mechanisms underlying thyroid cancer immune escape
can lead to the identification of new molecular targets and/or efficacy biomarkers. For this …

[HTML][HTML] Immune landscape of thyroid cancers: new insights

E Menicali, M Guzzetti, S Morelli, S Moretti… - Frontiers in …, 2021 - frontiersin.org
Immune system plays a key role in cancer prevention as well as in its initiation and
progression. During multistep development of tumors, cells must acquire the capability to …

Papillary thyroid carcinoma behavior: clues in the tumor microenvironment

K Bergdorf, DC Ferguson, M Mehrad… - Endocrine-Related …, 2019 - erc.bioscientifica.com
The prevalence of thyroid carcinoma is increasing and represents the most common
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …

Identification of gene co-expression modules and hub genes associated with lymph node metastasis of papillary thyroid cancer

T Zhai, D Muhanhali, X Jia, Z Wu, Z Cai, Y Ling - Endocrine, 2019 - Springer
Papillary thyroid cancer (PTC) is the most prevalent histological type among thyroid cancers,
and some patients are at a high risk for recurrent disease or even death. Identification for the …

[HTML][HTML] Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma

T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The tumor microenvironment (TME) plays a pivotal role in cancer progression in
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …