Lipid nanoparticles (LNPs) are capable of delivering messenger ribonucleic acid (mRNA)
efficiently and systemically as a result of both particle composition and architecture. The …

Conspectus Lipid nanoparticles (LNPs) are a type of lipid vesicles that possess a
homogeneous lipid core. These vesicles are widely used in small-molecule drug and …

Ionizable lipid‐based nanoparticles (LNPs) are the most advanced non‐viral drug delivery
systems for RNA therapeutics and vaccines. However, cell type‐specific, extrahepatic mRNA …

Lipid nanoparticle (LNP) packaged mRNA vaccines have been deployed against infectious
diseases such as COVID-19, yet their structural features remain unclear. Cholesterol, a …

Lipid nanoparticles (LNPs) represent the leading concept for mRNA delivery. Unsaturated
lipids play important roles in nature with potential for mRNA therapeutics, but are difficult to …

A central goal of chemical and drug delivery sciences is to maximize the therapeutic efficacy
of a given drug at the lowest possible dose. Here, we report a generalizable strategy that …

Conspectus After decades of extensive fundamental studies and clinical trials, lipid
nanoparticles (LNPs) have demonstrated effective mRNA delivery such as the Moderna and …

Recently, lipid nanoparticles (LNPs) have attracted attention due to their emergent use for
COVID‐19 mRNA vaccines. The success of LNPs can be attributed to ionizable lipids, which …

Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Lipid nanoparticles (LNPs) are effective vehicles to deliver mRNA vaccines and
therapeutics. It has been challenging to assess mRNA packaging characteristics in LNPs …