Chronic treatment with antidepressants increases neurogenesis in the adult hippocampus.
This increase in the production of new neurons may be required for the behavioral effects of …

Serotonergic antidepressant drugs have been commonly used to treat mood and anxiety
disorders, and increasing evidence suggests potential use of these drugs beyond current …

BACKGROUND: Fluoxetine stimulates proliferation of progenitor cells in the dentate gyrus of
the adult hippocampus. There are suggestions that this action may underlie the therapeutic …

New neurons are generated in the adult hippocampus of many species including rodents,
monkeys, and humans. Conditions associated with major depression, such as social stress …

Depression constitutes a widespread condition observed in elderly patients. Recently, it was
found that several drugs employed in therapies against depression stimulate hippocampal …

All classes of antidepressants increase hippocampal cell proliferation and neurogenesis,
which contributes, in part, to the behavioral actions of these treatments. Among …

The continuous generation of new neurons in the adult hippocampus exhibits remarkable
plasticity. Decreased neurogenesis is thought to underlie depression‐like behaviors, and …

The formation of new neurons continues into adult life in the dentate gyrus of the rat
hippocampus, as in many other species. Neurogenesis itself turns out to be highly labile …

Chronic treatments with selective serotonin reuptake inhibitors (SSRIs) have been shown to
increase hippocampal neurogenesis. However, it is not known whether SSRIs impact the …

Neurogenesis has been implicated in antidepressant drug action and animal models of
depression, suggesting that proliferating cells play a role in psychiatric disorders. Similar …