This book provides a comprehensive view of research in lens developmental biology,
emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that …

This review gives a brief account of the main processes of lens development, including
induction, morphogenesis, differentiation and growth. It describes what is known about the …

Millions are rendered blind or exhibit visual impairment due to pathologies of the lens of the
eye. Lens research therefore addresses the direct need to gain insights into the cellular and …

The factors that regulate the size of organs to ensure that they fit within an organism are not
well understood. A simple organ, the ocular lens serves as a useful model with which to …

Lens-cell differentiation occurs at a fairly early stage of embryogenesis and results in very
simple tissue architecture. These features allow the embryonic lens to provide a paradigm of …

In this paper, the more recent literature pertaining to differentiation in the developing
vertebrate lens is reviewed in relation to previous work. The literature reviewed reveals that …

Regulation of cell proliferation is a critical aspect of the development of multicellular
organisms. The ocular lens is an excellent model system in which to unravel the …

The lens of the vertebrate eye is an astonishing organ, crystal-clear and perfectly shaped to
focus the incoming light onto the retina. Its physical appearance is totally unlike that of any …

Ocular lens development represents an advantageous system in which to study regulatory
mechanisms governing cell fate decisions, extracellular signaling, cell and tissue …

The eye and lens represent excellent models to understand embryonic development at
cellular and molecular levels. Initial 3D formation of the eye depends on a reciprocal …